ZnS quantum dots derived a reagentless uric acid biosensor

Fenfen Zhang; Chenxin Li; Xiaohua Li; Xiaoli Wang; Qiao Wan; Yuezhong Xian; Litong Jin; Katsunobu Yamamoto

doi:10.1016/j.talanta.2005.07.051

ZnS quantum dots derived a reagentless uric acid biosensor

Fenfen Zhang
, Chenxin Li
, Xiaohua Li
, Xiaoli Wang
, Qiao Wan
, Yuezhong Xian
, Litong Jin^*
, Katsunobu Yamamoto

^*此作品的通讯作者

East China Normal University
BAS Co., Ltd.

科研成果: 期刊稿件 › 文章 › 同行评审

82 引用（Scopus）

摘要

A reagentless amperometric uric acid biosensor based on zinc sulfide (ZnS) quantum dots (QDs) was firstly developed. It could detect uric acid without the presence of an electron mediator. The carboxyl group functionalized ZnS QDs were synthesized, and they were soluble biocompatible and conductive. ZnS QDs conjugates could provide increased enzyme binding sites, which may result in higher enzyme loading. Thus, the proposed uricase/ZnS QDs/l-cys biosensor exhibited higher amperometric response compared to the one without QDs (uricase/l-cys biosensor). In addition, there was little AA interference. It showed a linear dependence on the uric acid concentration ranging from 5.0 × 10^-6 to 2.0 × 10^-3 mol L^-1 with a detection limit of 2.0 × 10^-6 mol L^-1 at 3σ.

源语言	英语
页（从-至）	1353-1358
页数	6
期刊	Talanta
卷	68
期	4
DOI	https://doi.org/10.1016/j.talanta.2005.07.051
出版状态	已出版 - 15 2月 2006

访问文件

10.1016/j.talanta.2005.07.051

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{cd263bc11d674c37a8f02a0452c3735a,

title = "ZnS quantum dots derived a reagentless uric acid biosensor",

abstract = "A reagentless amperometric uric acid biosensor based on zinc sulfide (ZnS) quantum dots (QDs) was firstly developed. It could detect uric acid without the presence of an electron mediator. The carboxyl group functionalized ZnS QDs were synthesized, and they were soluble biocompatible and conductive. ZnS QDs conjugates could provide increased enzyme binding sites, which may result in higher enzyme loading. Thus, the proposed uricase/ZnS QDs/l-cys biosensor exhibited higher amperometric response compared to the one without QDs (uricase/l-cys biosensor). In addition, there was little AA interference. It showed a linear dependence on the uric acid concentration ranging from 5.0 × 10-6 to 2.0 × 10-3 mol L-1 with a detection limit of 2.0 × 10-6 mol L-1 at 3σ.",

keywords = "Reagentless biosensor, Uric acid, Uricase, ZnS quantum dots",

author = "Fenfen Zhang and Chenxin Li and Xiaohua Li and Xiaoli Wang and Qiao Wan and Yuezhong Xian and Litong Jin and Katsunobu Yamamoto",

year = "2006",

month = feb,

day = "15",

doi = "10.1016/j.talanta.2005.07.051",

language = "英语",

volume = "68",

pages = "1353--1358",

journal = "Talanta",

issn = "0039-9140",

publisher = "Elsevier B.V.",

number = "4",

}

TY - JOUR

T1 - ZnS quantum dots derived a reagentless uric acid biosensor

AU - Zhang, Fenfen

AU - Li, Chenxin

AU - Li, Xiaohua

AU - Wang, Xiaoli

AU - Wan, Qiao

AU - Xian, Yuezhong

AU - Jin, Litong

AU - Yamamoto, Katsunobu

PY - 2006/2/15

Y1 - 2006/2/15

N2 - A reagentless amperometric uric acid biosensor based on zinc sulfide (ZnS) quantum dots (QDs) was firstly developed. It could detect uric acid without the presence of an electron mediator. The carboxyl group functionalized ZnS QDs were synthesized, and they were soluble biocompatible and conductive. ZnS QDs conjugates could provide increased enzyme binding sites, which may result in higher enzyme loading. Thus, the proposed uricase/ZnS QDs/l-cys biosensor exhibited higher amperometric response compared to the one without QDs (uricase/l-cys biosensor). In addition, there was little AA interference. It showed a linear dependence on the uric acid concentration ranging from 5.0 × 10-6 to 2.0 × 10-3 mol L-1 with a detection limit of 2.0 × 10-6 mol L-1 at 3σ.

AB - A reagentless amperometric uric acid biosensor based on zinc sulfide (ZnS) quantum dots (QDs) was firstly developed. It could detect uric acid without the presence of an electron mediator. The carboxyl group functionalized ZnS QDs were synthesized, and they were soluble biocompatible and conductive. ZnS QDs conjugates could provide increased enzyme binding sites, which may result in higher enzyme loading. Thus, the proposed uricase/ZnS QDs/l-cys biosensor exhibited higher amperometric response compared to the one without QDs (uricase/l-cys biosensor). In addition, there was little AA interference. It showed a linear dependence on the uric acid concentration ranging from 5.0 × 10-6 to 2.0 × 10-3 mol L-1 with a detection limit of 2.0 × 10-6 mol L-1 at 3σ.

KW - Reagentless biosensor

KW - Uric acid

KW - Uricase

KW - ZnS quantum dots

UR - https://www.scopus.com/pages/publications/30744463535

U2 - 10.1016/j.talanta.2005.07.051

DO - 10.1016/j.talanta.2005.07.051

M3 - 文章

AN - SCOPUS:30744463535

SN - 0039-9140

VL - 68

SP - 1353

EP - 1358

JO - Talanta

JF - Talanta

IS - 4

ER -

ZnS quantum dots derived a reagentless uric acid biosensor

摘要

访问文件

其它文件与链接

指纹

引用此