摘要
How pattern recognition receptors NOD1 and NOD2 sense bacterial muropeptides from extracellular bacteria to drive keratinocyte inflammation remains unclear. In this issue of Immunity, Bharadwaj et al. show that the solute carrier 46A2 (SLC46A2) delivers DAP-muropeptides into the cytosol to drive NOD1 activation in keratinocytes and elicit skin inflammation during psoriasis.
| 源语言 | 英语 |
|---|---|
| 页(从-至) | 897-900 |
| 页数 | 4 |
| 期刊 | Immunity |
| 卷 | 56 |
| 期 | 5 |
| DOI |
|
| 出版状态 | 已出版 - 9 5月 2023 |
联合国可持续发展目标
此成果有助于实现下列可持续发展目标:
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可持续发展目标 3 良好健康与福祉
指纹
探究 'When SLC46A2 delivers cargo into keratinocytes' 的科研主题。它们共同构成独一无二的指纹。引用此
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