Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles

Chang Lei; Chun Xu; Amanda Nouwens; Chengzhong Yu

doi:10.1039/c6tb01023g

Ultrasensitive ELISA⁺ enhanced by dendritic mesoporous silica nanoparticles

Chang Lei
, Chun Xu
, Amanda Nouwens
, Chengzhong Yu^*

^*此作品的通讯作者

University of Queensland

科研成果: 期刊稿件 › 文章 › 同行评审

46 引用（Scopus）

摘要

An ultrasensitive enzyme-linked immunosorbent assay (ELISA⁺) has been developed by using dendritic mesoporous silica nanoparticles (DMSNs) with high horseradish peroxidase (HRP) loading and easily accessible pore channels for signal amplification. A 2000 times enhancement of detection sensitivity compared to a commercial ELISA kit for insulin detection in serum is achieved.

源语言	英语
页（从-至）	4975-4979
页数	5
期刊	Journal of Materials Chemistry B
卷	4
期	29
DOI	https://doi.org/10.1039/c6tb01023g
出版状态	已出版 - 2016
已对外发布	是

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title = "Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles",

abstract = "An ultrasensitive enzyme-linked immunosorbent assay (ELISA+) has been developed by using dendritic mesoporous silica nanoparticles (DMSNs) with high horseradish peroxidase (HRP) loading and easily accessible pore channels for signal amplification. A 2000 times enhancement of detection sensitivity compared to a commercial ELISA kit for insulin detection in serum is achieved.",

author = "Chang Lei and Chun Xu and Amanda Nouwens and Chengzhong Yu",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2016.",

year = "2016",

doi = "10.1039/c6tb01023g",

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T1 - Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles

AU - Lei, Chang

AU - Xu, Chun

AU - Nouwens, Amanda

AU - Yu, Chengzhong

PY - 2016

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N2 - An ultrasensitive enzyme-linked immunosorbent assay (ELISA+) has been developed by using dendritic mesoporous silica nanoparticles (DMSNs) with high horseradish peroxidase (HRP) loading and easily accessible pore channels for signal amplification. A 2000 times enhancement of detection sensitivity compared to a commercial ELISA kit for insulin detection in serum is achieved.

AB - An ultrasensitive enzyme-linked immunosorbent assay (ELISA+) has been developed by using dendritic mesoporous silica nanoparticles (DMSNs) with high horseradish peroxidase (HRP) loading and easily accessible pore channels for signal amplification. A 2000 times enhancement of detection sensitivity compared to a commercial ELISA kit for insulin detection in serum is achieved.

UR - https://www.scopus.com/pages/publications/84979501932

U2 - 10.1039/c6tb01023g

DO - 10.1039/c6tb01023g

M3 - 文章

AN - SCOPUS:84979501932

SN - 2050-750X

VL - 4

SP - 4975

EP - 4979

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

IS - 29

ER -

Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles

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Ultrasensitive ELISA⁺ enhanced by dendritic mesoporous silica nanoparticles