Tuberoside M, a new cytotoxic spirostanol saponin from the seeds of Allium tuberosum

Sheng Min Sang; Min Liang Zou; Xiong Wen Zhang; Ai Na Lao; Zhong Liang Chen

doi:10.1080/10286020290019721

Tuberoside M, a new cytotoxic spirostanol saponin from the seeds of Allium tuberosum

Sheng Min Sang
, Min Liang Zou
, Xiong Wen Zhang
, Ai Na Lao^*
, Zhong Liang Chen

^*此作品的通讯作者

Chinese Academy of Sciences

科研成果: 期刊稿件 › 文章 › 同行评审

17 引用（Scopus）

摘要

Tuberoside M (1), isolated from the seeds of Allium tuberosum, shows a significant inhibitory effect on the growth of the human promyelocytic leukemia cell line (HL-60) with IC₅₀ value of 6.8 μg/ml. On the basis of spectral data and chemical reaction, its structure was established as (25S)-5β-spirostane-1β,3β-diol 3-O-α-L-rhamnopyranosyl-(1 → 4)-β-D-glucopyranoside.

源语言	英语
页（从-至）	67-70
页数	4
期刊	Journal of Asian Natural Products Research
卷	4
期	1
DOI	https://doi.org/10.1080/10286020290019721
出版状态	已出版 - 2002
已对外发布	是

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@article{edcb68fb84ef4d5191968d02abff62b4,

title = "Tuberoside M, a new cytotoxic spirostanol saponin from the seeds of Allium tuberosum",

abstract = "Tuberoside M (1), isolated from the seeds of Allium tuberosum, shows a significant inhibitory effect on the growth of the human promyelocytic leukemia cell line (HL-60) with IC50 value of 6.8 μg/ml. On the basis of spectral data and chemical reaction, its structure was established as (25S)-5β-spirostane-1β,3β-diol 3-O-α-L-rhamnopyranosyl-(1 → 4)-β-D-glucopyranoside.",

keywords = "Allium tuberosum, HL-60, Spirostanol saponin, Tuberoside M",

author = "Sang, \{Sheng Min\} and Zou, \{Min Liang\} and Zhang, \{Xiong Wen\} and Lao, \{Ai Na\} and Chen, \{Zhong Liang\}",

year = "2002",

doi = "10.1080/10286020290019721",

language = "英语",

volume = "4",

pages = "67--70",

journal = "Journal of Asian Natural Products Research",

issn = "1028-6020",

publisher = "Taylor and Francis Ltd.",

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T1 - Tuberoside M, a new cytotoxic spirostanol saponin from the seeds of Allium tuberosum

AU - Sang, Sheng Min

AU - Zou, Min Liang

AU - Zhang, Xiong Wen

AU - Lao, Ai Na

AU - Chen, Zhong Liang

PY - 2002

Y1 - 2002

N2 - Tuberoside M (1), isolated from the seeds of Allium tuberosum, shows a significant inhibitory effect on the growth of the human promyelocytic leukemia cell line (HL-60) with IC50 value of 6.8 μg/ml. On the basis of spectral data and chemical reaction, its structure was established as (25S)-5β-spirostane-1β,3β-diol 3-O-α-L-rhamnopyranosyl-(1 → 4)-β-D-glucopyranoside.

AB - Tuberoside M (1), isolated from the seeds of Allium tuberosum, shows a significant inhibitory effect on the growth of the human promyelocytic leukemia cell line (HL-60) with IC50 value of 6.8 μg/ml. On the basis of spectral data and chemical reaction, its structure was established as (25S)-5β-spirostane-1β,3β-diol 3-O-α-L-rhamnopyranosyl-(1 → 4)-β-D-glucopyranoside.

KW - Allium tuberosum

KW - HL-60

KW - Spirostanol saponin

KW - Tuberoside M

UR - https://www.scopus.com/pages/publications/0036240456

U2 - 10.1080/10286020290019721

DO - 10.1080/10286020290019721

M3 - 文章

C2 - 11995668

AN - SCOPUS:0036240456

SN - 1028-6020

VL - 4

SP - 67

EP - 70

JO - Journal of Asian Natural Products Research

JF - Journal of Asian Natural Products Research

IS - 1

ER -

Tuberoside M, a new cytotoxic spirostanol saponin from the seeds of Allium tuberosum

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