Thiazolidinediones: A novel class of drugs for the prevention of diabetic nephropathy?

F. Zheng; Y. Guan

doi:10.1038/sj.ki.5002557

Thiazolidinediones: A novel class of drugs for the prevention of diabetic nephropathy?

F. Zheng
, Y. Guan^*

^*此作品的通讯作者

Icahn School of Medicine at Mount Sinai
Peking University
Vanderbilt University

科研成果: 期刊稿件 › 评论/辩论

29 引用（Scopus）

摘要

Diabetic nephropathy is the leading cause of end-stage renal disease. Novel preventive measures for diabetic renal complications are urgently needed. Miyazaki et al. report that rosiglitazone, a thiazolidinedione insulin sensitizer and a potent peroxisome proliferator-activated receptor γ agonist, not only effectively improves glycemic control but also halts progression of albuminuria in type 2 diabetic patients with early-stage diabetic nephropathy. These findings could offer a new prevention of diabetic nephropathy in insulin-resistant diabetic patients.

源语言	英语
页（从-至）	1301-1303
页数	3
期刊	Kidney International
卷	72
期	11
DOI	https://doi.org/10.1038/sj.ki.5002557
出版状态	已出版 - 12月 2007
已对外发布	是

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

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title = "Thiazolidinediones: A novel class of drugs for the prevention of diabetic nephropathy?",

abstract = "Diabetic nephropathy is the leading cause of end-stage renal disease. Novel preventive measures for diabetic renal complications are urgently needed. Miyazaki et al. report that rosiglitazone, a thiazolidinedione insulin sensitizer and a potent peroxisome proliferator-activated receptor γ agonist, not only effectively improves glycemic control but also halts progression of albuminuria in type 2 diabetic patients with early-stage diabetic nephropathy. These findings could offer a new prevention of diabetic nephropathy in insulin-resistant diabetic patients.",

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AU - Guan, Y.

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N2 - Diabetic nephropathy is the leading cause of end-stage renal disease. Novel preventive measures for diabetic renal complications are urgently needed. Miyazaki et al. report that rosiglitazone, a thiazolidinedione insulin sensitizer and a potent peroxisome proliferator-activated receptor γ agonist, not only effectively improves glycemic control but also halts progression of albuminuria in type 2 diabetic patients with early-stage diabetic nephropathy. These findings could offer a new prevention of diabetic nephropathy in insulin-resistant diabetic patients.

AB - Diabetic nephropathy is the leading cause of end-stage renal disease. Novel preventive measures for diabetic renal complications are urgently needed. Miyazaki et al. report that rosiglitazone, a thiazolidinedione insulin sensitizer and a potent peroxisome proliferator-activated receptor γ agonist, not only effectively improves glycemic control but also halts progression of albuminuria in type 2 diabetic patients with early-stage diabetic nephropathy. These findings could offer a new prevention of diabetic nephropathy in insulin-resistant diabetic patients.

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DO - 10.1038/sj.ki.5002557

M3 - 评论/辩论

C2 - 18004308

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Thiazolidinediones: A novel class of drugs for the prevention of diabetic nephropathy?

摘要

联合国可持续发展目标

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