跳到主要导航 跳到搜索 跳到主要内容

Thiadiazole: A new family of intercalative photonuclease with electron transfer and radical mechanisms

  • Yonggang Li
  • , Yufang Xu
  • , Xuhong Qian*
  • , Baoyuan Qu
  • *此作品的通讯作者
  • East China University of Science and Technology
  • Dalian University of Technology

科研成果: 期刊稿件文章同行评审

摘要

A new family of photonuclease, thiadiazole-naphthalimide were synthesized and evaluated. Thiadiazole group was incorporated for the first time. These compounds intercalated into DNA efficiently and damaged DNA as low as 10 μM photochemically. Mechanism experiment showed that electron transfer and radicals were involved.

源语言英语
页(从-至)3513-3515
页数3
期刊Bioorganic and Medicinal Chemistry Letters
13
20
DOI
出版状态已出版 - 20 10月 2003
已对外发布

学术指纹

探究 'Thiadiazole: A new family of intercalative photonuclease with electron transfer and radical mechanisms' 的科研主题。它们共同构成独一无二的学术指纹。

引用此