The chemistry and biology of nakiterpiosin - C-nor-D-homosteroids

Shuanhu Gao; Qiaoling Wang; Gelin Wang; Brett Lomenick; Jie Liu; Chih Wei Fan; Lih Wen Deng; Jing Huang; Lawrence Lum; Chuo Chen

doi:10.1055/S-0031-1290460

The chemistry and biology of nakiterpiosin - C-nor-D-homosteroids

Shuanhu Gao
, Qiaoling Wang
, Gelin Wang
, Brett Lomenick
, Jie Liu
, Chih Wei Fan
, Lih Wen Deng
, Jing Huang
, Lawrence Lum
, Chuo Chen

University of Texas Southwestern Medical Center
University of California at Los Angeles
National University of Singapore

科研成果: 期刊稿件 › 文章 › 同行评审

10 引用（Scopus）

摘要

Isolated from the sponge Terpios hoshinota that causes coral black disease, nakiterpiosin was the first C-nor-D-homosteroid discovered from a marine source. We provide in this account an overview of the chemistry and biology of this natural product. We also include a short history of the synthesis of C-nor-D-homosteroids and the results of some unpublished biological studies of nakiterpiosin.

源语言	英语
文章编号	ST-2012-A0436-A
页（从-至）	2298-2310
页数	13
期刊	Synlett
卷	23
期	16
DOI	https://doi.org/10.1055/S-0031-1290460
出版状态	已出版 - 2012
已对外发布	是

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 14 水下生物

访问文件

10.1055/S-0031-1290460

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{30741c39847a41368167e0e7bcec88ca,

title = "The chemistry and biology of nakiterpiosin - C-nor-D-homosteroids",

abstract = "Isolated from the sponge Terpios hoshinota that causes coral black disease, nakiterpiosin was the first C-nor-D-homosteroid discovered from a marine source. We provide in this account an overview of the chemistry and biology of this natural product. We also include a short history of the synthesis of C-nor-D-homosteroids and the results of some unpublished biological studies of nakiterpiosin.",

keywords = "Hedgehog signaling, Natural products, Steroids, Total synthesis, Tubulin",

author = "Shuanhu Gao and Qiaoling Wang and Gelin Wang and Brett Lomenick and Jie Liu and Fan, \{Chih Wei\} and Deng, \{Lih Wen\} and Jing Huang and Lawrence Lum and Chuo Chen",

year = "2012",

doi = "10.1055/S-0031-1290460",

language = "英语",

volume = "23",

pages = "2298--2310",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "16",

}

TY - JOUR

T1 - The chemistry and biology of nakiterpiosin - C-nor-D-homosteroids

AU - Gao, Shuanhu

AU - Wang, Qiaoling

AU - Wang, Gelin

AU - Lomenick, Brett

AU - Liu, Jie

AU - Fan, Chih Wei

AU - Deng, Lih Wen

AU - Huang, Jing

AU - Lum, Lawrence

AU - Chen, Chuo

PY - 2012

Y1 - 2012

N2 - Isolated from the sponge Terpios hoshinota that causes coral black disease, nakiterpiosin was the first C-nor-D-homosteroid discovered from a marine source. We provide in this account an overview of the chemistry and biology of this natural product. We also include a short history of the synthesis of C-nor-D-homosteroids and the results of some unpublished biological studies of nakiterpiosin.

AB - Isolated from the sponge Terpios hoshinota that causes coral black disease, nakiterpiosin was the first C-nor-D-homosteroid discovered from a marine source. We provide in this account an overview of the chemistry and biology of this natural product. We also include a short history of the synthesis of C-nor-D-homosteroids and the results of some unpublished biological studies of nakiterpiosin.

KW - Hedgehog signaling

KW - Natural products

KW - Steroids

KW - Total synthesis

KW - Tubulin

UR - https://www.scopus.com/pages/publications/84866111349

U2 - 10.1055/S-0031-1290460

DO - 10.1055/S-0031-1290460

M3 - 文章

AN - SCOPUS:84866111349

SN - 0936-5214

VL - 23

SP - 2298

EP - 2310

JO - Synlett

JF - Synlett

IS - 16

M1 - ST-2012-A0436-A

ER -

The chemistry and biology of nakiterpiosin - C-nor-D-homosteroids

摘要

联合国可持续发展目标

访问文件

其它文件与链接

指纹

引用此