Synthesis of indoline-fused eight-membered azaheterocycles through Zn-catalyzed dearomatization of indoles and subsequent base-promoted C-C activation

Yuanyang Mu; Yang Yuan; Ye Wang; Murong Xu; Ye Feng; Yulei Zhao; Yanzhong Li

doi:10.1039/d0ob01626h

Synthesis of indoline-fused eight-membered azaheterocycles through Zn-catalyzed dearomatization of indoles and subsequent base-promoted C-C activation

Yuanyang Mu
, Yang Yuan
, Ye Wang
, Murong Xu
, Ye Feng
, Yulei Zhao^*
, Yanzhong Li^*

^*此作品的通讯作者

化学与分子工程学院

East China Normal University
Qufu Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

7 引用（Scopus）

摘要

A cascade reaction involving the Zn-catalyzed dearomatization of indoles, base-promoted ring-expansion and intramolecular SNAr reaction has been developed. This process realized a novel, atom economical and efficient synthesis of indoline-fused eight-membered azaheterocycles in a one pot manner.

源语言	英语
页（从-至）	6916-6926
页数	11
期刊	Organic and Biomolecular Chemistry
卷	18
期	35
DOI	https://doi.org/10.1039/d0ob01626h
出版状态	已出版 - 21 9月 2020

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title = "Synthesis of indoline-fused eight-membered azaheterocycles through Zn-catalyzed dearomatization of indoles and subsequent base-promoted C-C activation",

abstract = "A cascade reaction involving the Zn-catalyzed dearomatization of indoles, base-promoted ring-expansion and intramolecular SNAr reaction has been developed. This process realized a novel, atom economical and efficient synthesis of indoline-fused eight-membered azaheterocycles in a one pot manner.",

author = "Yuanyang Mu and Yang Yuan and Ye Wang and Murong Xu and Ye Feng and Yulei Zhao and Yanzhong Li",

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T1 - Synthesis of indoline-fused eight-membered azaheterocycles through Zn-catalyzed dearomatization of indoles and subsequent base-promoted C-C activation

AU - Mu, Yuanyang

AU - Yuan, Yang

AU - Wang, Ye

AU - Xu, Murong

AU - Feng, Ye

AU - Zhao, Yulei

AU - Li, Yanzhong

PY - 2020/9/21

Y1 - 2020/9/21

N2 - A cascade reaction involving the Zn-catalyzed dearomatization of indoles, base-promoted ring-expansion and intramolecular SNAr reaction has been developed. This process realized a novel, atom economical and efficient synthesis of indoline-fused eight-membered azaheterocycles in a one pot manner.

AB - A cascade reaction involving the Zn-catalyzed dearomatization of indoles, base-promoted ring-expansion and intramolecular SNAr reaction has been developed. This process realized a novel, atom economical and efficient synthesis of indoline-fused eight-membered azaheterocycles in a one pot manner.

UR - https://www.scopus.com/pages/publications/85091192195

U2 - 10.1039/d0ob01626h

DO - 10.1039/d0ob01626h

M3 - 文章

C2 - 32869825

AN - SCOPUS:85091192195

SN - 1477-0520

VL - 18

SP - 6916

EP - 6926

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 35

ER -

Synthesis of indoline-fused eight-membered azaheterocycles through Zn-catalyzed dearomatization of indoles and subsequent base-promoted C-C activation

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