Synthesis of 9-allyl-10-hydroxycamptothecin via Suzuki reaction

Yu Luo; Shanbao Yu; Qingqing Huang; Wei Lu

doi:10.1002/jhet.1549

Synthesis of 9-allyl-10-hydroxycamptothecin via Suzuki reaction

Yu Luo
, Shanbao Yu
, Qingqing Huang
, Wei Lu

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

3 引用（Scopus）

摘要

A facile and eco-friendly approach for synthesizing 9-allyl-10- hydroxycamptothecin (2), a key intermediate for the preparation of camptothecin analogs, is described. The product was obtained in good yield and high purity (≥99% HPLC) under mild Suzuki reaction condition.

源语言	英语
页（从-至）	1133-1136
页数	4
期刊	Journal of Heterocyclic Chemistry
卷	51
期	4
DOI	https://doi.org/10.1002/jhet.1549
出版状态	已出版 - 7月 2014

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title = "Synthesis of 9-allyl-10-hydroxycamptothecin via Suzuki reaction",

abstract = "A facile and eco-friendly approach for synthesizing 9-allyl-10- hydroxycamptothecin (2), a key intermediate for the preparation of camptothecin analogs, is described. The product was obtained in good yield and high purity (≥99\% HPLC) under mild Suzuki reaction condition.",

author = "Yu Luo and Shanbao Yu and Qingqing Huang and Wei Lu",

year = "2014",

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AU - Huang, Qingqing

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N2 - A facile and eco-friendly approach for synthesizing 9-allyl-10- hydroxycamptothecin (2), a key intermediate for the preparation of camptothecin analogs, is described. The product was obtained in good yield and high purity (≥99% HPLC) under mild Suzuki reaction condition.

AB - A facile and eco-friendly approach for synthesizing 9-allyl-10- hydroxycamptothecin (2), a key intermediate for the preparation of camptothecin analogs, is described. The product was obtained in good yield and high purity (≥99% HPLC) under mild Suzuki reaction condition.

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M3 - 文章

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Synthesis of 9-allyl-10-hydroxycamptothecin via Suzuki reaction

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