Synthesis of 1,1-Diboron Alkanes via Diborylation of Unactivated Primary C(sp3)-H Bonds Enabled by AsPh3/Iridium Catalysis

Wenqi Liu; Zhenlu Shen; Senmiao Xu

doi:10.6023/cjoc202111032

Synthesis of 1,1-Diboron Alkanes via Diborylation of Unactivated Primary C(sp³)-H Bonds Enabled by AsPh₃/Iridium Catalysis

投稿的翻译标题: 三苯基砷/铱催化的非活化一级碳氢键的双硼化反应合成1,1-偕二硼烷

Wenqi Liu
, Zhenlu Shen^*
, Senmiao Xu^*

^*此作品的通讯作者

Zhejiang University of Technology
CAS - Lanzhou Institute of Chemical Physics

科研成果: 期刊稿件 › 文章 › 同行评审

7 引用（Scopus）

摘要

The AsPh₃/iridium catalyzed diborylation of unactivated primary C(sp³)-H bonds using pyrazoles as directing groups was disclosed. This method could tolerate a variety of functional groups, affording a vast array of 1,1-diboron alkanes in moderate to good yields. The synthetic utility of the current method on a gram-scale reaction for further functionalization was also demonstrated.

投稿的翻译标题	三苯基砷/铱催化的非活化一级碳氢键的双硼化反应合成1,1-偕二硼烷
源语言	英语
页（从-至）	1101-1110
页数	10
期刊	Chinese Journal of Organic Chemistry
卷	42
期	4
DOI	https://doi.org/10.6023/cjoc202111032
出版状态	已出版 - 4月 2022
已对外发布	是

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title = "Synthesis of 1,1-Diboron Alkanes via Diborylation of Unactivated Primary C(sp3)-H Bonds Enabled by AsPh3/Iridium Catalysis",

abstract = "The AsPh3/iridium catalyzed diborylation of unactivated primary C(sp3)-H bonds using pyrazoles as directing groups was disclosed. This method could tolerate a variety of functional groups, affording a vast array of 1,1-diboron alkanes in moderate to good yields. The synthetic utility of the current method on a gram-scale reaction for further functionalization was also demonstrated.",

keywords = "C-H borylation, Iridium, Organoboron, Synthetic methods",

author = "Wenqi Liu and Zhenlu Shen and Senmiao Xu",

note = "Publisher Copyright: {\textcopyright} 2022 Chinese Chemical Society \& SIOC, CAS.",

year = "2022",

month = apr,

doi = "10.6023/cjoc202111032",

language = "英语",

volume = "42",

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T1 - Synthesis of 1,1-Diboron Alkanes via Diborylation of Unactivated Primary C(sp3)-H Bonds Enabled by AsPh3/Iridium Catalysis

AU - Liu, Wenqi

AU - Shen, Zhenlu

AU - Xu, Senmiao

PY - 2022/4

Y1 - 2022/4

N2 - The AsPh3/iridium catalyzed diborylation of unactivated primary C(sp3)-H bonds using pyrazoles as directing groups was disclosed. This method could tolerate a variety of functional groups, affording a vast array of 1,1-diboron alkanes in moderate to good yields. The synthetic utility of the current method on a gram-scale reaction for further functionalization was also demonstrated.

AB - The AsPh3/iridium catalyzed diborylation of unactivated primary C(sp3)-H bonds using pyrazoles as directing groups was disclosed. This method could tolerate a variety of functional groups, affording a vast array of 1,1-diboron alkanes in moderate to good yields. The synthetic utility of the current method on a gram-scale reaction for further functionalization was also demonstrated.

KW - C-H borylation

KW - Iridium

KW - Organoboron

KW - Synthetic methods

UR - https://www.scopus.com/pages/publications/85130463261

U2 - 10.6023/cjoc202111032

DO - 10.6023/cjoc202111032

M3 - 文章

AN - SCOPUS:85130463261

SN - 0253-2786

VL - 42

SP - 1101

EP - 1110

JO - Chinese Journal of Organic Chemistry

JF - Chinese Journal of Organic Chemistry

IS - 4

ER -

Synthesis of 1,1-Diboron Alkanes via Diborylation of Unactivated Primary C(sp3)-H Bonds Enabled by AsPh3/Iridium Catalysis

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Synthesis of 1,1-Diboron Alkanes via Diborylation of Unactivated Primary C(sp³)-H Bonds Enabled by AsPh₃/Iridium Catalysis