Straightforward Stereoselective Synthesis of Seven-Membered Oxa-Bridged Rings through in Situ Generated Cycloheptenol Derivatives

Mengdan Wang; Liqiang Yin; Lu Cheng; Yajie Yang; Yanzhong Li

doi:10.1021/acs.joc.1c01648

Straightforward Stereoselective Synthesis of Seven-Membered Oxa-Bridged Rings through in Situ Generated Cycloheptenol Derivatives

Mengdan Wang
, Liqiang Yin
, Lu Cheng
, Yajie Yang
, Yanzhong Li^*

^*此作品的通讯作者

化学与分子工程学院

East China Normal University
Ministry of Education of the People's Republic of China

科研成果: 期刊稿件 › 文章 › 同行评审

16 引用（Scopus）

摘要

An iodine-mediated stereoselective synthesis of seven-membered oxa-bridged rings via in situ generated cycloheptenols was reported. This process was realized through the combination of C-C σ-bond cleavage and C-O bond-forming reactions in a one-pot fashion from simple and easily accessible raw materials. The formation of carbon radicals initiated by I2 was the key to the reaction.

源语言	英语
页（从-至）	12956-12963
页数	8
期刊	Journal of Organic Chemistry
卷	86
期	18
DOI	https://doi.org/10.1021/acs.joc.1c01648
出版状态	已出版 - 17 9月 2021

访问文件

10.1021/acs.joc.1c01648

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{caf14373c9cb4dbc9a25e59453223b3d,

title = "Straightforward Stereoselective Synthesis of Seven-Membered Oxa-Bridged Rings through in Situ Generated Cycloheptenol Derivatives",

abstract = "An iodine-mediated stereoselective synthesis of seven-membered oxa-bridged rings via in situ generated cycloheptenols was reported. This process was realized through the combination of C-C σ-bond cleavage and C-O bond-forming reactions in a one-pot fashion from simple and easily accessible raw materials. The formation of carbon radicals initiated by I2 was the key to the reaction.",

author = "Mengdan Wang and Liqiang Yin and Lu Cheng and Yajie Yang and Yanzhong Li",

note = "Publisher Copyright: {\textcopyright} ",

year = "2021",

month = sep,

day = "17",

doi = "10.1021/acs.joc.1c01648",

language = "英语",

volume = "86",

pages = "12956--12963",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "18",

}

TY - JOUR

T1 - Straightforward Stereoselective Synthesis of Seven-Membered Oxa-Bridged Rings through in Situ Generated Cycloheptenol Derivatives

AU - Wang, Mengdan

AU - Yin, Liqiang

AU - Cheng, Lu

AU - Yang, Yajie

AU - Li, Yanzhong

PY - 2021/9/17

Y1 - 2021/9/17

N2 - An iodine-mediated stereoselective synthesis of seven-membered oxa-bridged rings via in situ generated cycloheptenols was reported. This process was realized through the combination of C-C σ-bond cleavage and C-O bond-forming reactions in a one-pot fashion from simple and easily accessible raw materials. The formation of carbon radicals initiated by I2 was the key to the reaction.

AB - An iodine-mediated stereoselective synthesis of seven-membered oxa-bridged rings via in situ generated cycloheptenols was reported. This process was realized through the combination of C-C σ-bond cleavage and C-O bond-forming reactions in a one-pot fashion from simple and easily accessible raw materials. The formation of carbon radicals initiated by I2 was the key to the reaction.

UR - https://www.scopus.com/pages/publications/85114513837

U2 - 10.1021/acs.joc.1c01648

DO - 10.1021/acs.joc.1c01648

M3 - 文章

AN - SCOPUS:85114513837

SN - 0022-3263

VL - 86

SP - 12956

EP - 12963

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 18

ER -

Straightforward Stereoselective Synthesis of Seven-Membered Oxa-Bridged Rings through in Situ Generated Cycloheptenol Derivatives

摘要

访问文件

其它文件与链接

学术指纹

引用此