Small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes

Jun Long Zhu; Zheng Xu; Yangyang Yang; Lin Xu

doi:10.1039/c9cc03299a

Small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes

Jun Long Zhu
, Zheng Xu
, Yangyang Yang
, Lin Xu^*

^*此作品的通讯作者

化学与分子工程学院

East China Normal University
Monash University
East China University of Science and Technology
Dalian University of Technology

科研成果: 期刊稿件 › 文章 › 同行评审

118 引用（Scopus）

摘要

In the past few years, the preparation of novel small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes has attracted considerable attention because of their wide applications in chemistry, biology, and medical science. This feature article summarizes the recent advances in the design and preparation of small-molecule fluorescent probes for specific detection of chemical species inside lysosomes. In addition, their properties and applications for the detection and imaging of pH, H₂O₂, HOCl, O₂^-, lipid peroxidation, H₂S, HSO₃^-, thiols, NO, ONOO^-, HNO, Zn²⁺, Cu²⁺, enzymes, etc. in lysosomes are discussed as well.

源语言	英语
页（从-至）	6629-6671
页数	43
期刊	Chemical Communications
卷	55
期	47
DOI	https://doi.org/10.1039/c9cc03299a
出版状态	已出版 - 2019

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title = "Small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes",

abstract = "In the past few years, the preparation of novel small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes has attracted considerable attention because of their wide applications in chemistry, biology, and medical science. This feature article summarizes the recent advances in the design and preparation of small-molecule fluorescent probes for specific detection of chemical species inside lysosomes. In addition, their properties and applications for the detection and imaging of pH, H2O2, HOCl, O2-, lipid peroxidation, H2S, HSO3-, thiols, NO, ONOO-, HNO, Zn2+, Cu2+, enzymes, etc. in lysosomes are discussed as well.",

author = "Zhu, \{Jun Long\} and Zheng Xu and Yangyang Yang and Lin Xu",

note = "Publisher Copyright: {\textcopyright} 2019 The Royal Society of Chemistry.",

year = "2019",

doi = "10.1039/c9cc03299a",

language = "英语",

volume = "55",

pages = "6629--6671",

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TY - JOUR

T1 - Small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes

AU - Zhu, Jun Long

AU - Xu, Zheng

AU - Yang, Yangyang

AU - Xu, Lin

PY - 2019

Y1 - 2019

N2 - In the past few years, the preparation of novel small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes has attracted considerable attention because of their wide applications in chemistry, biology, and medical science. This feature article summarizes the recent advances in the design and preparation of small-molecule fluorescent probes for specific detection of chemical species inside lysosomes. In addition, their properties and applications for the detection and imaging of pH, H2O2, HOCl, O2-, lipid peroxidation, H2S, HSO3-, thiols, NO, ONOO-, HNO, Zn2+, Cu2+, enzymes, etc. in lysosomes are discussed as well.

AB - In the past few years, the preparation of novel small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes has attracted considerable attention because of their wide applications in chemistry, biology, and medical science. This feature article summarizes the recent advances in the design and preparation of small-molecule fluorescent probes for specific detection of chemical species inside lysosomes. In addition, their properties and applications for the detection and imaging of pH, H2O2, HOCl, O2-, lipid peroxidation, H2S, HSO3-, thiols, NO, ONOO-, HNO, Zn2+, Cu2+, enzymes, etc. in lysosomes are discussed as well.

UR - https://www.scopus.com/pages/publications/85066875268

U2 - 10.1039/c9cc03299a

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M3 - 文章

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AN - SCOPUS:85066875268

SN - 1359-7345

VL - 55

SP - 6629

EP - 6671

JO - Chemical Communications

JF - Chemical Communications

IS - 47

ER -

Small-molecule fluorescent probes for specific detection and imaging of chemical species inside lysosomes

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