Reversible redox of NADH and NAD + at a hybrid lipid bilayer membrane using ubiquinone

Wei Ma; Da Wei Li; Todd C. Sutherland; Yang Li; Yi Tao Long; Hong Yuan Chen

doi:10.1021/ja204014s

Reversible redox of NADH and NAD ⁺ at a hybrid lipid bilayer membrane using ubiquinone

Wei Ma
, Da Wei Li
, Todd C. Sutherland
, Yang Li
, Yi Tao Long^*
, Hong Yuan Chen

^*此作品的通讯作者

East China University of Science and Technology
University of Calgary
Nanjing University

科研成果: 期刊稿件 › 文章 › 同行评审

71 引用（Scopus）

摘要

Here, we report the reversible interconversion between NADH and NAD ⁺ at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.

源语言	英语
页（从-至）	12366-12369
页数	4
期刊	Journal of the American Chemical Society
卷	133
期	32
DOI	https://doi.org/10.1021/ja204014s
出版状态	已出版 - 17 8月 2011
已对外发布	是

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10.1021/ja204014s

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abstract = "Here, we report the reversible interconversion between NADH and NAD + at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.",

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AU - Long, Yi Tao

AU - Chen, Hong Yuan

PY - 2011/8/17

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N2 - Here, we report the reversible interconversion between NADH and NAD + at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.

AB - Here, we report the reversible interconversion between NADH and NAD + at a low overpotential, which is in part mediated by ubiquinone embedded in a biomimetic membrane to mimic the initial stages of respiration. This system can be used as a platform to examine biologically relevant electroactive molecules embedded in a natural membrane environment and provide new insights into the mechanism of biological redox cycling.

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DO - 10.1021/ja204014s

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JF - Journal of the American Chemical Society

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ER -

Reversible redox of NADH and NAD + at a hybrid lipid bilayer membrane using ubiquinone

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Reversible redox of NADH and NAD ⁺ at a hybrid lipid bilayer membrane using ubiquinone