Research Progresses in Single Molecule Enzymology

Yan XU; Le Le SUN; Yan Jing GAO; Wei Wei QIN; Tian Huan PENG; Di LI

doi:10.1016/S1872-2040(16)60957-X

Research Progresses in Single Molecule Enzymology

Yan XU
, Le Le SUN
, Yan Jing GAO
, Wei Wei QIN
, Tian Huan PENG
, Di LI^*

^*此作品的通讯作者

Chinese Academy of Sciences

科研成果: 期刊稿件 › 文献综述 › 同行评审

1 引用（Scopus）

摘要

The advent of single molecule imaging technologies in 1990s made the dynamics of single molecule enzyme catalysis be successfully probed in real time in vitro. Ever since then, single molecule enzymology entered the golden age of rapid developing. Individual features of single enzyme molecule hidden in the overall average were discovered, and many new catalytic mechanisms were proposed. Single molecule enzymology sheds light on the dynamic interactions between enzyme and substrate or product, deepening the understanding of biochemical reactions.

源语言	英语
页（从-至）	1437-1446
页数	10
期刊	Chinese Journal of Analytical Chemistry
卷	44
期	9
DOI	https://doi.org/10.1016/S1872-2040(16)60957-X
出版状态	已出版 - 9月 2016
已对外发布	是

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@article{b45eedc87a5b4de9a4ff948cc5b7c0c5,

title = "Research Progresses in Single Molecule Enzymology",

abstract = "The advent of single molecule imaging technologies in 1990s made the dynamics of single molecule enzyme catalysis be successfully probed in real time in vitro. Ever since then, single molecule enzymology entered the golden age of rapid developing. Individual features of single enzyme molecule hidden in the overall average were discovered, and many new catalytic mechanisms were proposed. Single molecule enzymology sheds light on the dynamic interactions between enzyme and substrate or product, deepening the understanding of biochemical reactions.",

keywords = "Enzyme, Fluorescence microscopy, Fluorescence resonance energy transfer, Review, Ribozyme, Single molecule",

author = "Yan XU and SUN, \{Le Le\} and GAO, \{Yan Jing\} and QIN, \{Wei Wei\} and PENG, \{Tian Huan\} and Di LI",

note = "Publisher Copyright: {\textcopyright} 2016 Changchun Institute of Applied Chemistry, Chinese Academy of Sciences",

year = "2016",

month = sep,

doi = "10.1016/S1872-2040(16)60957-X",

language = "英语",

volume = "44",

pages = "1437--1446",

journal = "Chinese Journal of Analytical Chemistry",

issn = "0253-3820",

publisher = "Chinese Academy of Sciences",

number = "9",

}

TY - JOUR

T1 - Research Progresses in Single Molecule Enzymology

AU - XU, Yan

AU - SUN, Le Le

AU - GAO, Yan Jing

AU - QIN, Wei Wei

AU - PENG, Tian Huan

AU - LI, Di

PY - 2016/9

Y1 - 2016/9

N2 - The advent of single molecule imaging technologies in 1990s made the dynamics of single molecule enzyme catalysis be successfully probed in real time in vitro. Ever since then, single molecule enzymology entered the golden age of rapid developing. Individual features of single enzyme molecule hidden in the overall average were discovered, and many new catalytic mechanisms were proposed. Single molecule enzymology sheds light on the dynamic interactions between enzyme and substrate or product, deepening the understanding of biochemical reactions.

AB - The advent of single molecule imaging technologies in 1990s made the dynamics of single molecule enzyme catalysis be successfully probed in real time in vitro. Ever since then, single molecule enzymology entered the golden age of rapid developing. Individual features of single enzyme molecule hidden in the overall average were discovered, and many new catalytic mechanisms were proposed. Single molecule enzymology sheds light on the dynamic interactions between enzyme and substrate or product, deepening the understanding of biochemical reactions.

KW - Enzyme

KW - Fluorescence microscopy

KW - Fluorescence resonance energy transfer

KW - Review

KW - Ribozyme

KW - Single molecule

UR - https://www.scopus.com/pages/publications/85044291449

U2 - 10.1016/S1872-2040(16)60957-X

DO - 10.1016/S1872-2040(16)60957-X

M3 - 文献综述

AN - SCOPUS:85044291449

SN - 0253-3820

VL - 44

SP - 1437

EP - 1446

JO - Chinese Journal of Analytical Chemistry

JF - Chinese Journal of Analytical Chemistry

IS - 9

ER -

Research Progresses in Single Molecule Enzymology

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