Research on DNA electrochemiluminescence biosensing

Electrochemiluminescence (ECL) signal is generated directly or indirectly by the electrochemical reactions. Due to its characteristics of high sensitivity, specificity, easy realization of integration, real-time and in-situ detection, ECL detection provides powerful research tools and methods in life sciences at molecular level. Research on deoxyribonucleic acid (DNA) is an extremely important aspect in life science and shows the significance in the areas of forensic identification, epidemic prevention and environmental monitoring, especially for the early diagnosis and treatment of diseases. DNA-ECL biosensing is considered as the most promising technology for DNA analysis and has been a hot research topic in the fields of biology and medicine. This review summarizes the research on DNA-ECL biosensing technologies in China in the recent five years. Also, we look into its research prospects.