Regulation of KiSS1 gene expression

Dali Li; Weishi Yu; Mingyao Liu

doi:10.1016/j.peptides.2008.09.025

Regulation of KiSS1 gene expression

Dali Li
, Weishi Yu
, Mingyao Liu^*

^*此作品的通讯作者

生命科学学院

East China Normal University
Texas A&M University

科研成果: 期刊稿件 › 文献综述 › 同行评审

22 引用（Scopus）

摘要

Kisspeptins are the protein products encoded by KiSS1 gene, an important tumor metastatic suppressor and pivotal master hormone of puberty. Although KiSS1 gene is expressed in both central and peripheral tissues, the molecular mechanisms that determine the temporal and spatial expression of KiSS1 gene are not well understood. This review provides an update on the latest studies and ideas about the expression of KiSS1 gene as a puberty gatekeeper and a metastasis suppressor, with special emphasis on the molecular mechanisms for the transcriptional regulation of KiSS1 gene expression.

源语言	英语
页（从-至）	130-138
页数	9
期刊	Peptides
卷	30
期	1
DOI	https://doi.org/10.1016/j.peptides.2008.09.025
出版状态	已出版 - 1月 2009

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title = "Regulation of KiSS1 gene expression",

abstract = "Kisspeptins are the protein products encoded by KiSS1 gene, an important tumor metastatic suppressor and pivotal master hormone of puberty. Although KiSS1 gene is expressed in both central and peripheral tissues, the molecular mechanisms that determine the temporal and spatial expression of KiSS1 gene are not well understood. This review provides an update on the latest studies and ideas about the expression of KiSS1 gene as a puberty gatekeeper and a metastasis suppressor, with special emphasis on the molecular mechanisms for the transcriptional regulation of KiSS1 gene expression.",

keywords = "Expression, GPR54, KiSS1, Transcriptional regulation",

author = "Dali Li and Weishi Yu and Mingyao Liu",

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AU - Yu, Weishi

AU - Liu, Mingyao

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AB - Kisspeptins are the protein products encoded by KiSS1 gene, an important tumor metastatic suppressor and pivotal master hormone of puberty. Although KiSS1 gene is expressed in both central and peripheral tissues, the molecular mechanisms that determine the temporal and spatial expression of KiSS1 gene are not well understood. This review provides an update on the latest studies and ideas about the expression of KiSS1 gene as a puberty gatekeeper and a metastasis suppressor, with special emphasis on the molecular mechanisms for the transcriptional regulation of KiSS1 gene expression.

KW - Expression

KW - GPR54

KW - KiSS1

KW - Transcriptional regulation

UR - https://www.scopus.com/pages/publications/57849113331

U2 - 10.1016/j.peptides.2008.09.025

DO - 10.1016/j.peptides.2008.09.025

M3 - 文献综述

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SN - 0196-9781

VL - 30

SP - 130

EP - 138

JO - Peptides

JF - Peptides

IS - 1

ER -

Regulation of KiSS1 gene expression

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