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Red emissive fluorescent probe for the rapid detection of selenocysteine

  • Panpan Zhang
  • , Ying Ding
  • , Weimin Liu*
  • , Guangle Niu
  • , Hongyan Zhang
  • , Jiechao Ge
  • , Jiasheng Wu
  • , Yanqing Li
  • , Pengfei Wang
  • *此作品的通讯作者
  • CAS - Technical Institute of Physics and Chemistry
  • Soochow University
  • University of Chinese Academy of Sciences

科研成果: 期刊稿件文章同行评审

摘要

A novel fluorescent probe O-hNRSel based on tetralin-xanthene fused dye O-hNR was designed and synthesized by introducing 2,4-dinitrobenzenesulfonate functionality. This probe is able to detect selenocysteine (Sec) with rapid response time (2 min) and a large fluorescence enhancement at 624 nm (124-fold). O-hNRSel exhibited selective response to Sec over many other analy and high sensitivity with the detection limit as low as 17 nM. Furthermore, O-hNRSel has been used for fluorescent imaging of Sec in living cells with good biocompatibility.

源语言英语
页(从-至)234-239
页数6
期刊Sensors and Actuators B: Chemical
264
DOI
出版状态已出版 - 1 7月 2018
已对外发布

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