Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations

Yexiang Zhang; Yufang Xu; Shaoying Tan; Lin Xu; Xuhong Qian

doi:10.1016/j.tetlet.2012.09.074

Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations

Yexiang Zhang
, Yufang Xu
, Shaoying Tan
, Lin Xu
, Xuhong Qian^*

^*此作品的通讯作者

East China University of Science and Technology

科研成果: 期刊稿件 › 文章 › 同行评审

12 引用（Scopus）

摘要

A new monoamine oxidase (MAO) fluorescent probe that displays response for both monoamine oxidase type-A (MAO-A) and monoamine oxidase type-B (MAO-B) is reported. This sensing platform does not require any additional enzymes or reagents. Furthermore, the probes have better sensitivity and shorter response time by comparison with similar probes, and have potentials in differentiation of MAO-A and MAO-B upon further optimization.

源语言	英语
页（从-至）	6881-6884
页数	4
期刊	Tetrahedron Letters
卷	53
期	51
DOI	https://doi.org/10.1016/j.tetlet.2012.09.074
出版状态	已出版 - 19 12月 2012
已对外发布	是

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10.1016/j.tetlet.2012.09.074

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title = "Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations",

abstract = "A new monoamine oxidase (MAO) fluorescent probe that displays response for both monoamine oxidase type-A (MAO-A) and monoamine oxidase type-B (MAO-B) is reported. This sensing platform does not require any additional enzymes or reagents. Furthermore, the probes have better sensitivity and shorter response time by comparison with similar probes, and have potentials in differentiation of MAO-A and MAO-B upon further optimization.",

keywords = "Coumarin derivatives, Fluorescent probes, Low concentrations, Monoamine oxidase type-B",

author = "Yexiang Zhang and Yufang Xu and Shaoying Tan and Lin Xu and Xuhong Qian",

year = "2012",

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day = "19",

doi = "10.1016/j.tetlet.2012.09.074",

language = "英语",

volume = "53",

pages = "6881--6884",

journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations

AU - Zhang, Yexiang

AU - Xu, Yufang

AU - Tan, Shaoying

AU - Xu, Lin

AU - Qian, Xuhong

PY - 2012/12/19

Y1 - 2012/12/19

N2 - A new monoamine oxidase (MAO) fluorescent probe that displays response for both monoamine oxidase type-A (MAO-A) and monoamine oxidase type-B (MAO-B) is reported. This sensing platform does not require any additional enzymes or reagents. Furthermore, the probes have better sensitivity and shorter response time by comparison with similar probes, and have potentials in differentiation of MAO-A and MAO-B upon further optimization.

AB - A new monoamine oxidase (MAO) fluorescent probe that displays response for both monoamine oxidase type-A (MAO-A) and monoamine oxidase type-B (MAO-B) is reported. This sensing platform does not require any additional enzymes or reagents. Furthermore, the probes have better sensitivity and shorter response time by comparison with similar probes, and have potentials in differentiation of MAO-A and MAO-B upon further optimization.

KW - Coumarin derivatives

KW - Fluorescent probes

KW - Low concentrations

KW - Monoamine oxidase type-B

UR - https://www.scopus.com/pages/publications/84869234492

U2 - 10.1016/j.tetlet.2012.09.074

DO - 10.1016/j.tetlet.2012.09.074

M3 - 文章

AN - SCOPUS:84869234492

SN - 0040-4039

VL - 53

SP - 6881

EP - 6884

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 51

ER -

Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations

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