Progress of Actinidia chinensis Planch. root extract (acRoots) in cancer immunity

Lingyan Wang; Zheng Li; Miaomiao Zhang; Qi Shen; Xuemei Zhang

doi:10.1002/ctd2.171

Progress of Actinidia chinensis Planch. root extract (acRoots) in cancer immunity

Lingyan Wang^*
, Zheng Li
, Miaomiao Zhang
, Qi Shen
, Xuemei Zhang^*

^*此作品的通讯作者

Fudan University

科研成果: 期刊稿件 › 文献综述 › 同行评审

摘要

Actinidia chinensis Planch. root extract (acRoots) is a famous Chinese traditional medicine used in the treatment of a variety of diseases, such as tumours and cardiovascular diseases, etc. However, its therapeutic mechanisms remain unclear. In this review, the biological features of acRoots and its chemical compositions are explored, including polysaccharides, triterpenes, phenols, flavonoids and so on. The pathogenesis of cancer involves not only genetic factors but also the microenvironment. Different types of immune cells, such as T cells, macrophages and neutrophils, play an essential role in cancer development, and acRoots was found to take part in modulating cancer immunity. Therefore, this article summarises its role in cancer immunity and unmasks the potential underlying mechanisms by incorporating our research on cancer immunity.

源语言	英语
文章编号	e171
期刊	Clinical and Translational Discovery
卷	3
期	1
DOI	https://doi.org/10.1002/ctd2.171
出版状态	已出版 - 2月 2023
已对外发布	是

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

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10.1002/ctd2.171

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title = "Progress of Actinidia chinensis Planch. root extract (acRoots) in cancer immunity",

abstract = "Actinidia chinensis Planch. root extract (acRoots) is a famous Chinese traditional medicine used in the treatment of a variety of diseases, such as tumours and cardiovascular diseases, etc. However, its therapeutic mechanisms remain unclear. In this review, the biological features of acRoots and its chemical compositions are explored, including polysaccharides, triterpenes, phenols, flavonoids and so on. The pathogenesis of cancer involves not only genetic factors but also the microenvironment. Different types of immune cells, such as T cells, macrophages and neutrophils, play an essential role in cancer development, and acRoots was found to take part in modulating cancer immunity. Therefore, this article summarises its role in cancer immunity and unmasks the potential underlying mechanisms by incorporating our research on cancer immunity.",

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AU - Zhang, Xuemei

PY - 2023/2

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N2 - Actinidia chinensis Planch. root extract (acRoots) is a famous Chinese traditional medicine used in the treatment of a variety of diseases, such as tumours and cardiovascular diseases, etc. However, its therapeutic mechanisms remain unclear. In this review, the biological features of acRoots and its chemical compositions are explored, including polysaccharides, triterpenes, phenols, flavonoids and so on. The pathogenesis of cancer involves not only genetic factors but also the microenvironment. Different types of immune cells, such as T cells, macrophages and neutrophils, play an essential role in cancer development, and acRoots was found to take part in modulating cancer immunity. Therefore, this article summarises its role in cancer immunity and unmasks the potential underlying mechanisms by incorporating our research on cancer immunity.

AB - Actinidia chinensis Planch. root extract (acRoots) is a famous Chinese traditional medicine used in the treatment of a variety of diseases, such as tumours and cardiovascular diseases, etc. However, its therapeutic mechanisms remain unclear. In this review, the biological features of acRoots and its chemical compositions are explored, including polysaccharides, triterpenes, phenols, flavonoids and so on. The pathogenesis of cancer involves not only genetic factors but also the microenvironment. Different types of immune cells, such as T cells, macrophages and neutrophils, play an essential role in cancer development, and acRoots was found to take part in modulating cancer immunity. Therefore, this article summarises its role in cancer immunity and unmasks the potential underlying mechanisms by incorporating our research on cancer immunity.

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M3 - 文献综述

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SN - 2768-0622

VL - 3

JO - Clinical and Translational Discovery

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ER -

Progress of Actinidia chinensis Planch. root extract (acRoots) in cancer immunity

摘要

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