Porous silicon-based oligonucleotide chips

Li Shao; Shaoqiang Chen; Jian Zhang; Jianzhong Zhu; Ziqiang Zhu; Bin Zhu

doi:10.1117/12.607477

Porous silicon-based oligonucleotide chips

Li Shao
, Shaoqiang Chen
, Jian Zhang
, Jianzhong Zhu
, Ziqiang Zhu^*
, Bin Zhu

^*此作品的通讯作者

通信与电子工程学院

East China Normal University

科研成果: 期刊稿件 › 会议文章 › 同行评审

摘要

A novel oligonucleotide chip with porous silicon / oxidized porous silicon (PS/OPS) as its substrate has been developed. The attachment rate and detection sensitivity were improved obviously due to enormous surface area of PS/OPS compared to the existing conventional techniques. No dependence of storage condition on the detection sensitivity is found (signals variation is within SD). Stability of the oligonucleotide chips is good.

源语言	英语
文章编号	124
页（从-至）	535-538
页数	4
期刊	Proceedings of SPIE - The International Society for Optical Engineering
卷	5774
DOI	https://doi.org/10.1117/12.607477
出版状态	已出版 - 2005
活动	Fifth International Conference on Thin Film Physics and Applications - Shanghai, 中国期限: 31 5月 2004 → 2 6月 2004

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title = "Porous silicon-based oligonucleotide chips",

abstract = "A novel oligonucleotide chip with porous silicon / oxidized porous silicon (PS/OPS) as its substrate has been developed. The attachment rate and detection sensitivity were improved obviously due to enormous surface area of PS/OPS compared to the existing conventional techniques. No dependence of storage condition on the detection sensitivity is found (signals variation is within SD). Stability of the oligonucleotide chips is good.",

keywords = "Attachment rate, DNA, Detection sensitivity, OPS, Oligonucleotide chip, PS, Porous silicon, Stability, Substrate",

author = "Li Shao and Shaoqiang Chen and Jian Zhang and Jianzhong Zhu and Ziqiang Zhu and Bin Zhu",

year = "2005",

doi = "10.1117/12.607477",

language = "英语",

volume = "5774",

pages = "535--538",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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note = "Fifth International Conference on Thin Film Physics and Applications ; Conference date: 31-05-2004 Through 02-06-2004",

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TY - JOUR

T1 - Porous silicon-based oligonucleotide chips

AU - Shao, Li

AU - Chen, Shaoqiang

AU - Zhang, Jian

AU - Zhu, Jianzhong

AU - Zhu, Ziqiang

AU - Zhu, Bin

PY - 2005

Y1 - 2005

N2 - A novel oligonucleotide chip with porous silicon / oxidized porous silicon (PS/OPS) as its substrate has been developed. The attachment rate and detection sensitivity were improved obviously due to enormous surface area of PS/OPS compared to the existing conventional techniques. No dependence of storage condition on the detection sensitivity is found (signals variation is within SD). Stability of the oligonucleotide chips is good.

AB - A novel oligonucleotide chip with porous silicon / oxidized porous silicon (PS/OPS) as its substrate has been developed. The attachment rate and detection sensitivity were improved obviously due to enormous surface area of PS/OPS compared to the existing conventional techniques. No dependence of storage condition on the detection sensitivity is found (signals variation is within SD). Stability of the oligonucleotide chips is good.

KW - Attachment rate

KW - DNA

KW - Detection sensitivity

KW - OPS

KW - Oligonucleotide chip

KW - PS

KW - Porous silicon

KW - Stability

KW - Substrate

UR - https://www.scopus.com/pages/publications/25844447638

U2 - 10.1117/12.607477

DO - 10.1117/12.607477

M3 - 会议文章

AN - SCOPUS:25844447638

SN - 0277-786X

VL - 5774

SP - 535

EP - 538

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

M1 - 124

T2 - Fifth International Conference on Thin Film Physics and Applications

Y2 - 31 May 2004 through 2 June 2004

ER -

Porous silicon-based oligonucleotide chips

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