Pattern recognition analysis of proteins using dna-decorated catalytic gold nanoparticles

Xiafeng Yang; Jiang Li; Hao Pei; Di Li; Yun Zhao; Jimin Gao; Jianxin Lu; Jiye Shi; Chunhai Fan; Qing Huang

doi:10.1002/smll.201202772

Pattern recognition analysis of proteins using dna-decorated catalytic gold nanoparticles

Xiafeng Yang
, Jiang Li
, Hao Pei
, Di Li
, Yun Zhao
, Jimin Gao
, Jianxin Lu
, Jiye Shi
, Chunhai Fan
, Qing Huang^*

^*此作品的通讯作者

College of Life Sciences
Chinese Academy of Sciences
Ministry of Education of the People's Republic of China
UCB Pharma

科研成果: 期刊稿件 › 文章 › 同行评审

61 引用（Scopus）

摘要

A label-free protein analysis strategy is based on patterns of gold nanoparticle (AuNP) growth. AuNPs pretreated with different oligonucleotides are challenged with various proteins. After Au reduction, the colorimetric patterns are processed with linear discriminant analysis. This method discriminates different proteins, or one protein of different concentrations, in mixed samples or even serum and urine.

源语言	英语
页（从-至）	2844-2849
页数	6
期刊	Small
卷	9
期	17
DOI	https://doi.org/10.1002/smll.201202772
出版状态	已出版 - 9 9月 2013
已对外发布	是

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title = "Pattern recognition analysis of proteins using dna-decorated catalytic gold nanoparticles",

abstract = "A label-free protein analysis strategy is based on patterns of gold nanoparticle (AuNP) growth. AuNPs pretreated with different oligonucleotides are challenged with various proteins. After Au reduction, the colorimetric patterns are processed with linear discriminant analysis. This method discriminates different proteins, or one protein of different concentrations, in mixed samples or even serum and urine.",

keywords = "biosensors, gold nanoparticles, oligonucleotides, pattern recognition, proteins",

author = "Xiafeng Yang and Jiang Li and Hao Pei and Di Li and Yun Zhao and Jimin Gao and Jianxin Lu and Jiye Shi and Chunhai Fan and Qing Huang",

year = "2013",

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T1 - Pattern recognition analysis of proteins using dna-decorated catalytic gold nanoparticles

AU - Yang, Xiafeng

AU - Li, Jiang

AU - Pei, Hao

AU - Li, Di

AU - Zhao, Yun

AU - Gao, Jimin

AU - Lu, Jianxin

AU - Shi, Jiye

AU - Fan, Chunhai

AU - Huang, Qing

PY - 2013/9/9

Y1 - 2013/9/9

N2 - A label-free protein analysis strategy is based on patterns of gold nanoparticle (AuNP) growth. AuNPs pretreated with different oligonucleotides are challenged with various proteins. After Au reduction, the colorimetric patterns are processed with linear discriminant analysis. This method discriminates different proteins, or one protein of different concentrations, in mixed samples or even serum and urine.

AB - A label-free protein analysis strategy is based on patterns of gold nanoparticle (AuNP) growth. AuNPs pretreated with different oligonucleotides are challenged with various proteins. After Au reduction, the colorimetric patterns are processed with linear discriminant analysis. This method discriminates different proteins, or one protein of different concentrations, in mixed samples or even serum and urine.

KW - biosensors

KW - gold nanoparticles

KW - oligonucleotides

KW - pattern recognition

KW - proteins

UR - https://www.scopus.com/pages/publications/84883518393

U2 - 10.1002/smll.201202772

DO - 10.1002/smll.201202772

M3 - 文章

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AN - SCOPUS:84883518393

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SP - 2844

EP - 2849

JO - Small

JF - Small

IS - 17

ER -

Pattern recognition analysis of proteins using dna-decorated catalytic gold nanoparticles

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