Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4 + 2] Annulation of 2 H-Isoindole Derivatives with Internal Alkynes

Tengfei Yao; Fang Zhang; Junliang Zhang; Lu Liu

doi:10.1021/acs.orglett.0c01643

Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4 + 2] Annulation of 2 H-Isoindole Derivatives with Internal Alkynes

Tengfei Yao
, Fang Zhang
, Junliang Zhang^*
, Lu Liu^*

^*此作品的通讯作者

化学与分子工程学院

科研成果: 期刊稿件 › 文章 › 同行评审

20 引用（Scopus）

摘要

Here, an interesting palladium-catalyzed intermolecular Heck-type dearomative [4 + 2] annulation of 2H-isoindole derivatives with internal alkynes has been developed, affording diverse polycyclic pyrrolidine scaffolds in good yield. This reaction is a useful method for the transformation of 2H-isoindole.

源语言	英语
页（从-至）	5063-5067
页数	5
期刊	Organic Letters
卷	22
期	13
DOI	https://doi.org/10.1021/acs.orglett.0c01643
出版状态	已出版 - 2 7月 2020

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10.1021/acs.orglett.0c01643

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title = "Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4 + 2] Annulation of 2 H-Isoindole Derivatives with Internal Alkynes",

abstract = "Here, an interesting palladium-catalyzed intermolecular Heck-type dearomative [4 + 2] annulation of 2H-isoindole derivatives with internal alkynes has been developed, affording diverse polycyclic pyrrolidine scaffolds in good yield. This reaction is a useful method for the transformation of 2H-isoindole.",

author = "Tengfei Yao and Fang Zhang and Junliang Zhang and Lu Liu",

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AU - Zhang, Junliang

AU - Liu, Lu

PY - 2020/7/2

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AB - Here, an interesting palladium-catalyzed intermolecular Heck-type dearomative [4 + 2] annulation of 2H-isoindole derivatives with internal alkynes has been developed, affording diverse polycyclic pyrrolidine scaffolds in good yield. This reaction is a useful method for the transformation of 2H-isoindole.

UR - https://www.scopus.com/pages/publications/85087027416

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Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4 + 2] Annulation of 2 H-Isoindole Derivatives with Internal Alkynes

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