Organocatalytic Michael addition of unprotected 3-substituted oxindoles to nitroolefins

Miao Ding; Feng Zhou; Zi Qing Qian; Jian Zhou

doi:10.1039/c004037a

Organocatalytic Michael addition of unprotected 3-substituted oxindoles to nitroolefins

Miao Ding
, Feng Zhou
, Zi Qing Qian
, Jian Zhou^*

^*此作品的通讯作者

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

78 引用（Scopus）

摘要

Quinidine was found to catalyze the Michael addition of unprotected 3-substituted oxindoles to nitroolefins in excellent yield and moderate to good diastereoselectivity. Bifunctional quinidine derived thiourea catalyst 10 could catalyze this reaction to afford the major diastereomer in up to 85% ee.

源语言	英语
页（从-至）	2912-2914
页数	3
期刊	Organic and Biomolecular Chemistry
卷	8
期	13
DOI	https://doi.org/10.1039/c004037a
出版状态	已出版 - 28 6月 2010

访问文件

10.1039/c004037a

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{fd6848f32c8e4bdf956f9a2b62e820de,

title = "Organocatalytic Michael addition of unprotected 3-substituted oxindoles to nitroolefins",

abstract = "Quinidine was found to catalyze the Michael addition of unprotected 3-substituted oxindoles to nitroolefins in excellent yield and moderate to good diastereoselectivity. Bifunctional quinidine derived thiourea catalyst 10 could catalyze this reaction to afford the major diastereomer in up to 85\% ee.",

author = "Miao Ding and Feng Zhou and Qian, \{Zi Qing\} and Jian Zhou",

year = "2010",

month = jun,

day = "28",

doi = "10.1039/c004037a",

language = "英语",

volume = "8",

pages = "2912--2914",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "13",

}

TY - JOUR

T1 - Organocatalytic Michael addition of unprotected 3-substituted oxindoles to nitroolefins

AU - Ding, Miao

AU - Zhou, Feng

AU - Qian, Zi Qing

AU - Zhou, Jian

PY - 2010/6/28

Y1 - 2010/6/28

N2 - Quinidine was found to catalyze the Michael addition of unprotected 3-substituted oxindoles to nitroolefins in excellent yield and moderate to good diastereoselectivity. Bifunctional quinidine derived thiourea catalyst 10 could catalyze this reaction to afford the major diastereomer in up to 85% ee.

AB - Quinidine was found to catalyze the Michael addition of unprotected 3-substituted oxindoles to nitroolefins in excellent yield and moderate to good diastereoselectivity. Bifunctional quinidine derived thiourea catalyst 10 could catalyze this reaction to afford the major diastereomer in up to 85% ee.

UR - https://www.scopus.com/pages/publications/77953757228

U2 - 10.1039/c004037a

DO - 10.1039/c004037a

M3 - 文章

C2 - 20473440

AN - SCOPUS:77953757228

SN - 1477-0520

VL - 8

SP - 2912

EP - 2914

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 13

ER -

Organocatalytic Michael addition of unprotected 3-substituted oxindoles to nitroolefins

摘要

访问文件

其它文件与链接

学术指纹

引用此