Organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position

Feng Zhou; Xing Ping Zeng; Chao Wang; Xiao Li Zhao; Jian Zhou

doi:10.1039/c3cc38819k

Organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position

Feng Zhou
, Xing Ping Zeng
, Chao Wang
, Xiao Li Zhao
, Jian Zhou^*

^*此作品的通讯作者

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

88 引用（Scopus）

摘要

We report the first organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position. Importantly, 3-thiooxindoles and 3-alkoxyoxindoles are demonstrated to be reactive nucleophiles for the development of catalytic asymmetric reactions for the first time.

源语言	英语
页（从-至）	2022-2024
页数	3
期刊	Chemical Communications
卷	49
期	20
DOI	https://doi.org/10.1039/c3cc38819k
出版状态	已出版 - 12 2月 2013

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10.1039/c3cc38819k

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title = "Organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position",

abstract = "We report the first organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position. Importantly, 3-thiooxindoles and 3-alkoxyoxindoles are demonstrated to be reactive nucleophiles for the development of catalytic asymmetric reactions for the first time.",

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T1 - Organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position

AU - Zhou, Feng

AU - Zeng, Xing Ping

AU - Wang, Chao

AU - Zhao, Xiao Li

AU - Zhou, Jian

PY - 2013/2/12

Y1 - 2013/2/12

N2 - We report the first organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position. Importantly, 3-thiooxindoles and 3-alkoxyoxindoles are demonstrated to be reactive nucleophiles for the development of catalytic asymmetric reactions for the first time.

AB - We report the first organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position. Importantly, 3-thiooxindoles and 3-alkoxyoxindoles are demonstrated to be reactive nucleophiles for the development of catalytic asymmetric reactions for the first time.

UR - https://www.scopus.com/pages/publications/84873692152

U2 - 10.1039/c3cc38819k

DO - 10.1039/c3cc38819k

M3 - 文章

C2 - 23370775

AN - SCOPUS:84873692152

SN - 1359-7345

VL - 49

SP - 2022

EP - 2024

JO - Chemical Communications

JF - Chemical Communications

IS - 20

ER -

Organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position

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