Ni-Catalyzed enantioselective reductive arylcyanation/cyclization of: N -(2-iodo-aryl) acrylamide

Guangzhu Wang; Chaoren Shen; Xinyi Ren; Kaiwu Dong

doi:10.1039/d1cc04996h

Ni-Catalyzed enantioselective reductive arylcyanation/cyclization of: N -(2-iodo-aryl) acrylamide

Guangzhu Wang
, Chaoren Shen
, Xinyi Ren
, Kaiwu Dong

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

14 引用（Scopus）

摘要

A Ni/(S,S)-BDPP-catalyzed intramolecular Heck cyclization of N-(2-iodo-aryl) acrylamide with 2-methyl-2-phenylmalononitrile was developed to give oxindoles with good enantioselectivities. We found that utilizing such an electrophilic cyanation reagent could tackle the deleterious effect of the coordinative cyanide ion in the asymmetric alkene arylcyanation.

源语言	英语
页（从-至）	1135-1138
页数	4
期刊	Chemical Communications
卷	58
期	8
DOI	https://doi.org/10.1039/d1cc04996h
出版状态	已出版 - 25 1月 2022

访问文件

10.1039/d1cc04996h

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{976a3d1472f9456fbf2cbcdb17286d44,

title = "Ni-Catalyzed enantioselective reductive arylcyanation/cyclization of: N -(2-iodo-aryl) acrylamide",

abstract = "A Ni/(S,S)-BDPP-catalyzed intramolecular Heck cyclization of N-(2-iodo-aryl) acrylamide with 2-methyl-2-phenylmalononitrile was developed to give oxindoles with good enantioselectivities. We found that utilizing such an electrophilic cyanation reagent could tackle the deleterious effect of the coordinative cyanide ion in the asymmetric alkene arylcyanation.",

author = "Guangzhu Wang and Chaoren Shen and Xinyi Ren and Kaiwu Dong",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2022",

month = jan,

day = "25",

doi = "10.1039/d1cc04996h",

language = "英语",

volume = "58",

pages = "1135--1138",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "8",

}

TY - JOUR

T1 - Ni-Catalyzed enantioselective reductive arylcyanation/cyclization of

T2 - N -(2-iodo-aryl) acrylamide

AU - Wang, Guangzhu

AU - Shen, Chaoren

AU - Ren, Xinyi

AU - Dong, Kaiwu

PY - 2022/1/25

Y1 - 2022/1/25

N2 - A Ni/(S,S)-BDPP-catalyzed intramolecular Heck cyclization of N-(2-iodo-aryl) acrylamide with 2-methyl-2-phenylmalononitrile was developed to give oxindoles with good enantioselectivities. We found that utilizing such an electrophilic cyanation reagent could tackle the deleterious effect of the coordinative cyanide ion in the asymmetric alkene arylcyanation.

AB - A Ni/(S,S)-BDPP-catalyzed intramolecular Heck cyclization of N-(2-iodo-aryl) acrylamide with 2-methyl-2-phenylmalononitrile was developed to give oxindoles with good enantioselectivities. We found that utilizing such an electrophilic cyanation reagent could tackle the deleterious effect of the coordinative cyanide ion in the asymmetric alkene arylcyanation.

UR - https://www.scopus.com/pages/publications/85123791534

U2 - 10.1039/d1cc04996h

DO - 10.1039/d1cc04996h

M3 - 文章

C2 - 34981092

AN - SCOPUS:85123791534

SN - 1359-7345

VL - 58

SP - 1135

EP - 1138

JO - Chemical Communications

JF - Chemical Communications

IS - 8

ER -

Ni-Catalyzed enantioselective reductive arylcyanation/cyclization of: N -(2-iodo-aryl) acrylamide

摘要

访问文件

其它文件与链接

指纹

引用此