Nanoparticles mimicking viral surface topography for enhanced cellular delivery

Yuting Niu; Meihua Yu; Sandy B. Hartono; Jie Yang; Hongyi Xu; Hongwei Zhang; Jun Zhang; Jin Zou; Annette Dexter; Wenyi Gu; Chengzhong Yu

doi:10.1002/adma.201302737

Nanoparticles mimicking viral surface topography for enhanced cellular delivery

Yuting Niu
, Meihua Yu
, Sandy B. Hartono
, Jie Yang
, Hongyi Xu
, Hongwei Zhang
, Jun Zhang
, Jin Zou
, Annette Dexter
, Wenyi Gu
, Chengzhong Yu^*

^*此作品的通讯作者

University of Queensland

科研成果: 期刊稿件 › 文章 › 同行评审

203 引用（Scopus）

摘要

Novel silica nanoparticles mimicking virus surface topography are prepared. It is demonstrated that increases in nanoscale surface roughness promote both binding of biomolecules and cellular uptake; thus, the cellular delivery efficiency is significantly increased (scale bars 20â€...μm).

源语言	英语
页（从-至）	6233-6237
页数	5
期刊	Advanced Materials
卷	25
期	43
DOI	https://doi.org/10.1002/adma.201302737
出版状态	已出版 - 20 11月 2013
已对外发布	是

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@article{a1562c352b374d8da168169325eab3e2,

title = "Nanoparticles mimicking viral surface topography for enhanced cellular delivery",

abstract = "Novel silica nanoparticles mimicking virus surface topography are prepared. It is demonstrated that increases in nanoscale surface roughness promote both binding of biomolecules and cellular uptake; thus, the cellular delivery efficiency is significantly increased (scale bars 20{\^a}€...μm).",

keywords = "biomimetic synthesis, drug delivery, nanoparticles, surface topography",

author = "Yuting Niu and Meihua Yu and Hartono, \{Sandy B.\} and Jie Yang and Hongyi Xu and Hongwei Zhang and Jun Zhang and Jin Zou and Annette Dexter and Wenyi Gu and Chengzhong Yu",

year = "2013",

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T1 - Nanoparticles mimicking viral surface topography for enhanced cellular delivery

AU - Niu, Yuting

AU - Yu, Meihua

AU - Hartono, Sandy B.

AU - Yang, Jie

AU - Xu, Hongyi

AU - Zhang, Hongwei

AU - Zhang, Jun

AU - Zou, Jin

AU - Dexter, Annette

AU - Gu, Wenyi

AU - Yu, Chengzhong

PY - 2013/11/20

Y1 - 2013/11/20

N2 - Novel silica nanoparticles mimicking virus surface topography are prepared. It is demonstrated that increases in nanoscale surface roughness promote both binding of biomolecules and cellular uptake; thus, the cellular delivery efficiency is significantly increased (scale bars 20â€...μm).

AB - Novel silica nanoparticles mimicking virus surface topography are prepared. It is demonstrated that increases in nanoscale surface roughness promote both binding of biomolecules and cellular uptake; thus, the cellular delivery efficiency is significantly increased (scale bars 20â€...μm).

KW - biomimetic synthesis

KW - drug delivery

KW - nanoparticles

KW - surface topography

UR - https://www.scopus.com/pages/publications/84888006928

U2 - 10.1002/adma.201302737

DO - 10.1002/adma.201302737

M3 - 文章

C2 - 23946251

AN - SCOPUS:84888006928

SN - 0935-9648

VL - 25

SP - 6233

EP - 6237

JO - Advanced Materials

JF - Advanced Materials

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ER -

Nanoparticles mimicking viral surface topography for enhanced cellular delivery

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