Multicomponent Synthesis of Unsymmetrical 4,5-Disubstituted Imidazolium Salts as N-Heterocyclic Carbene Precursors: Applications in Palladium-Catalyzed Cross-Coupling Reactions

Jiwei Wang; Xiang Cheng; Ye Liu; Jun Zhang

doi:10.1021/acs.joc.1c00075

Multicomponent Synthesis of Unsymmetrical 4,5-Disubstituted Imidazolium Salts as N-Heterocyclic Carbene Precursors: Applications in Palladium-Catalyzed Cross-Coupling Reactions

Jiwei Wang
, Xiang Cheng
, Ye Liu^*
, Jun Zhang^*

^*此作品的通讯作者

化学与分子工程学院

East China Normal University
East China University of Science and Technology

科研成果: 期刊稿件 › 文章 › 同行评审

7 引用（Scopus）

摘要

Various novel (a)chiral 4,5-disubstituted 1-aryl-3-alkyl-imidazolium salts were synthesized via the multicomponent reaction of diketone derivatives, sterically congested arylamines, and alkylamines. Moreover, two novel unsymmetrical bulky cycloalkyl-based NHC-Pd complexes proved highly active as catalysts for Suzuki-Miyaura and Negishi cross-coupling reactions.

源语言	英语
页（从-至）	6278-6288
页数	11
期刊	Journal of Organic Chemistry
卷	86
期	9
DOI	https://doi.org/10.1021/acs.joc.1c00075
出版状态	已出版 - 7 5月 2021

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abstract = "Various novel (a)chiral 4,5-disubstituted 1-aryl-3-alkyl-imidazolium salts were synthesized via the multicomponent reaction of diketone derivatives, sterically congested arylamines, and alkylamines. Moreover, two novel unsymmetrical bulky cycloalkyl-based NHC-Pd complexes proved highly active as catalysts for Suzuki-Miyaura and Negishi cross-coupling reactions.",

author = "Jiwei Wang and Xiang Cheng and Ye Liu and Jun Zhang",

year = "2021",

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doi = "10.1021/acs.joc.1c00075",

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T1 - Multicomponent Synthesis of Unsymmetrical 4,5-Disubstituted Imidazolium Salts as N-Heterocyclic Carbene Precursors

T2 - Applications in Palladium-Catalyzed Cross-Coupling Reactions

AU - Wang, Jiwei

AU - Cheng, Xiang

AU - Liu, Ye

AU - Zhang, Jun

PY - 2021/5/7

Y1 - 2021/5/7

N2 - Various novel (a)chiral 4,5-disubstituted 1-aryl-3-alkyl-imidazolium salts were synthesized via the multicomponent reaction of diketone derivatives, sterically congested arylamines, and alkylamines. Moreover, two novel unsymmetrical bulky cycloalkyl-based NHC-Pd complexes proved highly active as catalysts for Suzuki-Miyaura and Negishi cross-coupling reactions.

AB - Various novel (a)chiral 4,5-disubstituted 1-aryl-3-alkyl-imidazolium salts were synthesized via the multicomponent reaction of diketone derivatives, sterically congested arylamines, and alkylamines. Moreover, two novel unsymmetrical bulky cycloalkyl-based NHC-Pd complexes proved highly active as catalysts for Suzuki-Miyaura and Negishi cross-coupling reactions.

UR - https://www.scopus.com/pages/publications/85106456976

U2 - 10.1021/acs.joc.1c00075

DO - 10.1021/acs.joc.1c00075

M3 - 文章

AN - SCOPUS:85106456976

SN - 0022-3263

VL - 86

SP - 6278

EP - 6288

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 9

ER -

Multicomponent Synthesis of Unsymmetrical 4,5-Disubstituted Imidazolium Salts as N-Heterocyclic Carbene Precursors: Applications in Palladium-Catalyzed Cross-Coupling Reactions

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