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MALDI in-source photooxidation reactions for online peptide tagging

  • Liang Qiao*
  • , Christophe Roussel
  • , Jingjing Wan
  • , Jilie Kong
  • , Pengyuan Yang
  • , Hubert H. Girault
  • , Baohong Liu
  • *此作品的通讯作者
  • Fudan University
  • Swiss Federal Institute of Technology Lausanne

科研成果: 期刊稿件文章同行评审

摘要

(Chemical Equation Presented) A TiO2 photoelectrode array has been designed to achieve efficient photoelectrochemical redox reactions with electron donors or acceptors during the laser desorption ionization process. By adding hydroquinone to a peptide mixture, the photoelectrochemically generated benzoquinone reacts with the cysteine residues to selectively form tagged cysteine-containing peptides, thus demonstrating that in-source oxidation reactions can be efficiently performed.

源语言英语
页(从-至)2646-2648
页数3
期刊Angewandte Chemie - International Edition
47
14
DOI
出版状态已出版 - 25 3月 2008
已对外发布

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