Ligand-Free Iridium-Catalyzed Dehydrogenative ortho C−H Borylation of Benzyl-2-Pyridines at Room Temperature

Yuhuan Yang; Qian Gao; Senmiao Xu

doi:10.1002/adsc.201801292

Ligand-Free Iridium-Catalyzed Dehydrogenative ortho C−H Borylation of Benzyl-2-Pyridines at Room Temperature

Yuhuan Yang
, Qian Gao
, Senmiao Xu^*

^*此作品的通讯作者

CAS - Lanzhou Institute of Chemical Physics
Hangzhou Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

21 引用（Scopus）

摘要

A convenient and ligand-free iridium-catalyzed dehydrogenative ortho C−H borylation of benzyl-2-pyridines has been developed. The reaction proceeds smoothly at room temperature using pinacolborane as a borylating reagent in the presence of catalytic amount of [IrOMe(COD)] ₂ . The reaction is compatible with many functional groups, providing a vast array of ortho borylated products in moderate to excellent yields with excellent selectivities. (Figure presented.).

源语言	英语
页（从-至）	858-862
页数	5
期刊	Advanced Synthesis and Catalysis
卷	361
期	4
DOI	https://doi.org/10.1002/adsc.201801292
出版状态	已出版 - 19 2月 2019
已对外发布	是

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@article{75e270bb09b545fa9fef74aa62dc6bae,

title = "Ligand-Free Iridium-Catalyzed Dehydrogenative ortho C−H Borylation of Benzyl-2-Pyridines at Room Temperature",

abstract = " A convenient and ligand-free iridium-catalyzed dehydrogenative ortho C−H borylation of benzyl-2-pyridines has been developed. The reaction proceeds smoothly at room temperature using pinacolborane as a borylating reagent in the presence of catalytic amount of [IrOMe(COD)] 2 . The reaction is compatible with many functional groups, providing a vast array of ortho borylated products in moderate to excellent yields with excellent selectivities. (Figure presented.).",

keywords = "C−H activation, borylation, iridium, organoboron, synthetic methods",

author = "Yuhuan Yang and Qian Gao and Senmiao Xu",

note = "Publisher Copyright: {\textcopyright} 2019 Wiley-VCH Verlag GmbH \& Co. KGaA, Weinheim",

year = "2019",

month = feb,

day = "19",

doi = "10.1002/adsc.201801292",

language = "英语",

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TY - JOUR

T1 - Ligand-Free Iridium-Catalyzed Dehydrogenative ortho C−H Borylation of Benzyl-2-Pyridines at Room Temperature

AU - Yang, Yuhuan

AU - Gao, Qian

AU - Xu, Senmiao

PY - 2019/2/19

Y1 - 2019/2/19

N2 - A convenient and ligand-free iridium-catalyzed dehydrogenative ortho C−H borylation of benzyl-2-pyridines has been developed. The reaction proceeds smoothly at room temperature using pinacolborane as a borylating reagent in the presence of catalytic amount of [IrOMe(COD)] 2 . The reaction is compatible with many functional groups, providing a vast array of ortho borylated products in moderate to excellent yields with excellent selectivities. (Figure presented.).

AB - A convenient and ligand-free iridium-catalyzed dehydrogenative ortho C−H borylation of benzyl-2-pyridines has been developed. The reaction proceeds smoothly at room temperature using pinacolborane as a borylating reagent in the presence of catalytic amount of [IrOMe(COD)] 2 . The reaction is compatible with many functional groups, providing a vast array of ortho borylated products in moderate to excellent yields with excellent selectivities. (Figure presented.).

KW - C−H activation

KW - borylation

KW - iridium

KW - organoboron

KW - synthetic methods

UR - https://www.scopus.com/pages/publications/85058952285

U2 - 10.1002/adsc.201801292

DO - 10.1002/adsc.201801292

M3 - 文章

AN - SCOPUS:85058952285

SN - 1615-4150

VL - 361

SP - 858

EP - 862

JO - Advanced Synthesis and Catalysis

JF - Advanced Synthesis and Catalysis

IS - 4

ER -

Ligand-Free Iridium-Catalyzed Dehydrogenative ortho C−H Borylation of Benzyl-2-Pyridines at Room Temperature

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