TY - JOUR
T1 - Laser-induced graphene interfaces for artificial taste and chemical perception
T2 - From interfacial transduction to high-dimensional interpretation
AU - Yin, Ying
AU - Wang, Xinyao
AU - Liu, Xingyu
AU - Wang, Yiming
AU - Zhang, Min
N1 - Publisher Copyright:
© 2026 Elsevier B.V.
PY - 2026/9
Y1 - 2026/9
N2 - Artificial taste systems are emerging as analytical platforms for complex liquid environments, where chemically meaningful information is encoded in multicomponent response patterns rather than individual analyte signals. Conventional electronic tongues, however, remain constrained by limited signal dimensionality, matrix-induced drift, and insufficient interpretability. Laser-induced graphene (LIG) interfaces provide a versatile route for constructing high-dimensional chemical perception platforms because their porous, defect-rich, and engineerable structures can convert heterogeneous interfacial interactions into multidimensional electrical responses. Within this broader family, LIG-FET and LIG-EGFET architectures represent important subfamilies because field-effect readout enables amplified, modular, and interface-sensitive transduction. In this review, we frame LIG-based artificial taste as a transition from target-specific detection to system-level chemical perception. We discuss how interfacial physics, LIG structural heterogeneity, surface engineering, electrochemical readout, and extended-gate architectures regulate chemical information generation and encoding capacity. We further analyze how data-driven models act as nonlinear decoders of electrical response manifolds, and why physics-informed learning is needed for robust, interpretable, and transferable chemical interpretation. We critically evaluate representative applications using an evidence-level framework that separates direct artificial-taste demonstrations from multiplexed biosensing, matrix-tolerant single-target sensing, and peripheral portable, self-powered, or microfluidic integration platforms. Finally, we propose reporting criteria and design principles for developing LIG-based chemical perception platforms from high-performance sensors toward robust artificial taste systems.
AB - Artificial taste systems are emerging as analytical platforms for complex liquid environments, where chemically meaningful information is encoded in multicomponent response patterns rather than individual analyte signals. Conventional electronic tongues, however, remain constrained by limited signal dimensionality, matrix-induced drift, and insufficient interpretability. Laser-induced graphene (LIG) interfaces provide a versatile route for constructing high-dimensional chemical perception platforms because their porous, defect-rich, and engineerable structures can convert heterogeneous interfacial interactions into multidimensional electrical responses. Within this broader family, LIG-FET and LIG-EGFET architectures represent important subfamilies because field-effect readout enables amplified, modular, and interface-sensitive transduction. In this review, we frame LIG-based artificial taste as a transition from target-specific detection to system-level chemical perception. We discuss how interfacial physics, LIG structural heterogeneity, surface engineering, electrochemical readout, and extended-gate architectures regulate chemical information generation and encoding capacity. We further analyze how data-driven models act as nonlinear decoders of electrical response manifolds, and why physics-informed learning is needed for robust, interpretable, and transferable chemical interpretation. We critically evaluate representative applications using an evidence-level framework that separates direct artificial-taste demonstrations from multiplexed biosensing, matrix-tolerant single-target sensing, and peripheral portable, self-powered, or microfluidic integration platforms. Finally, we propose reporting criteria and design principles for developing LIG-based chemical perception platforms from high-performance sensors toward robust artificial taste systems.
KW - Artificial taste
KW - Chemical perception
KW - Electronic tongue
KW - Extended-gate FET
KW - Laser-induced graphene
KW - Laser-induced graphene interfaces
KW - Machine learning
UR - https://www.scopus.com/pages/publications/105041061521
U2 - 10.1016/j.trac.2026.118948
DO - 10.1016/j.trac.2026.118948
M3 - 文献综述
AN - SCOPUS:105041061521
SN - 0165-9936
VL - 202
JO - TrAC - Trends in Analytical Chemistry
JF - TrAC - Trends in Analytical Chemistry
M1 - 118948
ER -