Iridium-Catalyzed γ-Selective Hydroboration of γ-Substituted Allylic Amides

Hongliang Zhao; Qian Gao; Yajuan Zhang; Panke Zhang; Senmiao Xu

doi:10.1021/acs.orglett.0c00977

Iridium-Catalyzed γ-Selective Hydroboration of γ-Substituted Allylic Amides

Hongliang Zhao
, Qian Gao
, Yajuan Zhang
, Panke Zhang^*
, Senmiao Xu

^*此作品的通讯作者

科研成果: 期刊稿件 › 文章 › 同行评审

14 引用（Scopus）

摘要

Reported here for the first time is the Ir-catalyzed γ-selective hydroboration of γ-substituted allylic amides under mild reaction conditions. A variety of functional groups could be compatible with reaction conditions, affording γ-branched amides in good yields with ≤97% γ-selectivity. We have also demonstrated that the obtained borylated products could be used in a series of C-O, C-F, C-Br, and C-C bond-forming reactions.

源语言	英语
页（从-至）	2861-2866
页数	6
期刊	Organic Letters
卷	22
期	7
DOI	https://doi.org/10.1021/acs.orglett.0c00977
出版状态	已出版 - 3 4月 2020
已对外发布	是

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abstract = "Reported here for the first time is the Ir-catalyzed γ-selective hydroboration of γ-substituted allylic amides under mild reaction conditions. A variety of functional groups could be compatible with reaction conditions, affording γ-branched amides in good yields with ≤97\% γ-selectivity. We have also demonstrated that the obtained borylated products could be used in a series of C-O, C-F, C-Br, and C-C bond-forming reactions.",

author = "Hongliang Zhao and Qian Gao and Yajuan Zhang and Panke Zhang and Senmiao Xu",

note = "Publisher Copyright: {\textcopyright} 2020 American Chemical Society.",

year = "2020",

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T1 - Iridium-Catalyzed γ-Selective Hydroboration of γ-Substituted Allylic Amides

AU - Zhao, Hongliang

AU - Gao, Qian

AU - Zhang, Yajuan

AU - Zhang, Panke

AU - Xu, Senmiao

PY - 2020/4/3

Y1 - 2020/4/3

N2 - Reported here for the first time is the Ir-catalyzed γ-selective hydroboration of γ-substituted allylic amides under mild reaction conditions. A variety of functional groups could be compatible with reaction conditions, affording γ-branched amides in good yields with ≤97% γ-selectivity. We have also demonstrated that the obtained borylated products could be used in a series of C-O, C-F, C-Br, and C-C bond-forming reactions.

AB - Reported here for the first time is the Ir-catalyzed γ-selective hydroboration of γ-substituted allylic amides under mild reaction conditions. A variety of functional groups could be compatible with reaction conditions, affording γ-branched amides in good yields with ≤97% γ-selectivity. We have also demonstrated that the obtained borylated products could be used in a series of C-O, C-F, C-Br, and C-C bond-forming reactions.

UR - https://www.scopus.com/pages/publications/85082510152

U2 - 10.1021/acs.orglett.0c00977

DO - 10.1021/acs.orglett.0c00977

M3 - 文章

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AN - SCOPUS:85082510152

SN - 1523-7060

VL - 22

SP - 2861

EP - 2866

JO - Organic Letters

JF - Organic Letters

IS - 7

ER -

Iridium-Catalyzed γ-Selective Hydroboration of γ-Substituted Allylic Amides

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