In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H+

Fan Zhao; Limin Zhang; Anwei Zhu; Guoyue Shi; Yang Tian

doi:10.1039/c5cc09540a

In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H⁺

Fan Zhao
, Limin Zhang
, Anwei Zhu
, Guoyue Shi^*
, Yang Tian

^*此作品的通讯作者

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

46 引用（Scopus）

摘要

pH plays an important role in the biochemical, ion-regulatory, or electrical machinery of nerve and glial cells, and is considered to be related to a number of degenerative diseases. Herein, we first develop a two-channel electrochemical ratiometric biosensor for local pH determination in a live rat brain, and report the accurate pH values in the different regions of live brains upon global cerebral ischemia.

源语言	英语
页（从-至）	3717-3720
页数	4
期刊	Chemical Communications
卷	52
期	18
DOI	https://doi.org/10.1039/c5cc09540a
出版状态	已出版 - 2016

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10.1039/c5cc09540a

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引用此

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title = "In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H+",

abstract = "pH plays an important role in the biochemical, ion-regulatory, or electrical machinery of nerve and glial cells, and is considered to be related to a number of degenerative diseases. Herein, we first develop a two-channel electrochemical ratiometric biosensor for local pH determination in a live rat brain, and report the accurate pH values in the different regions of live brains upon global cerebral ischemia.",

author = "Fan Zhao and Limin Zhang and Anwei Zhu and Guoyue Shi and Yang Tian",

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AU - Zhao, Fan

AU - Zhang, Limin

AU - Zhu, Anwei

AU - Shi, Guoyue

AU - Tian, Yang

PY - 2016

Y1 - 2016

N2 - pH plays an important role in the biochemical, ion-regulatory, or electrical machinery of nerve and glial cells, and is considered to be related to a number of degenerative diseases. Herein, we first develop a two-channel electrochemical ratiometric biosensor for local pH determination in a live rat brain, and report the accurate pH values in the different regions of live brains upon global cerebral ischemia.

AB - pH plays an important role in the biochemical, ion-regulatory, or electrical machinery of nerve and glial cells, and is considered to be related to a number of degenerative diseases. Herein, we first develop a two-channel electrochemical ratiometric biosensor for local pH determination in a live rat brain, and report the accurate pH values in the different regions of live brains upon global cerebral ischemia.

UR - https://www.scopus.com/pages/publications/84959231754

U2 - 10.1039/c5cc09540a

DO - 10.1039/c5cc09540a

M3 - 文章

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SN - 1359-7345

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EP - 3720

JO - Chemical Communications

JF - Chemical Communications

IS - 18

ER -

In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H+

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In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H⁺