TY - JOUR
T1 - Hydrotalcite-like Materials as Catalyst for the Conjugate Addition of Amines to Electron Deficient Alkenes
AU - CHEN, Lu
AU - ZHU, Juan
AU - WU, Haihong
AU - YANG, Jianguo
AU - WANG, Jian
PY - 2009/10
Y1 - 2009/10
N2 - The novel efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes. A series of hydrotalcite-like materials were synthesized as catalyst for the conjugate addition of amines and alkenes. After optimizing the reaction conditions, ZnAl-LDHs (3:1) was chosen as the best catalyst for the reaction. The results showed that the catalyst worked very well for the conjugate addition of amines to electron deficient alkenes with the excellent yields in several minutes. Operational simplicity, no solvent, low cost of the catalyst, high yields, reusability, excellent chemoselectivity, wide applicability are the key features of this method.
AB - The novel efficient procedure has been developed for the conjugate addition of amines to electron deficient alkenes. A series of hydrotalcite-like materials were synthesized as catalyst for the conjugate addition of amines and alkenes. After optimizing the reaction conditions, ZnAl-LDHs (3:1) was chosen as the best catalyst for the reaction. The results showed that the catalyst worked very well for the conjugate addition of amines to electron deficient alkenes with the excellent yields in several minutes. Operational simplicity, no solvent, low cost of the catalyst, high yields, reusability, excellent chemoselectivity, wide applicability are the key features of this method.
KW - chemoselectivity
KW - conjugate addition
KW - hydrotalcite-like material
KW - solvent-free synthesis
UR - https://www.scopus.com/pages/publications/71849085214
U2 - 10.1016/S1004-9541(08)60290-6
DO - 10.1016/S1004-9541(08)60290-6
M3 - 文章
AN - SCOPUS:71849085214
SN - 1004-9541
VL - 17
SP - 875
EP - 878
JO - Chinese Journal of Chemical Engineering
JF - Chinese Journal of Chemical Engineering
IS - 5
ER -