Highly enantioselective michael addition of 3-arylthio- and 3-alkylthiooxindoles to nitroolefins catalyzed by a simple cinchona alkaloid derived phosphoramide

Wei Ming Gao; Jin Sheng Yu; Yu Lei Zhao; Yun Lin Liu; Feng Zhou; Hai Hong Wu; Jian Zhou

doi:10.1039/c4cc06417h

Highly enantioselective michael addition of 3-arylthio- and 3-alkylthiooxindoles to nitroolefins catalyzed by a simple cinchona alkaloid derived phosphoramide

Wei Ming Gao
, Jin Sheng Yu
, Yu Lei Zhao
, Yun Lin Liu
, Feng Zhou
, Hai Hong Wu^*
, Jian Zhou

^*此作品的通讯作者

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

47 引用（Scopus）

摘要

A new cinchona alkaloid derived bifunctional tertiary amine-phosphoramide C1e is identified as a highly enantioselective catalyst for Michael addition of both unprotected 3-arylthio- and 3-alkylthiooxindoles to nitroolefins. The phosphoramide moiety of C1e plays an indispensable role in this reaction.

源语言	英语
页（从-至）	15179-15182
页数	4
期刊	Chemical Communications
卷	50
期	96
DOI	https://doi.org/10.1039/c4cc06417h
出版状态	已出版 - 6 11月 2014

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abstract = "A new cinchona alkaloid derived bifunctional tertiary amine-phosphoramide C1e is identified as a highly enantioselective catalyst for Michael addition of both unprotected 3-arylthio- and 3-alkylthiooxindoles to nitroolefins. The phosphoramide moiety of C1e plays an indispensable role in this reaction.",

author = "Gao, \{Wei Ming\} and Yu, \{Jin Sheng\} and Zhao, \{Yu Lei\} and Liu, \{Yun Lin\} and Feng Zhou and Wu, \{Hai Hong\} and Jian Zhou",

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T1 - Highly enantioselective michael addition of 3-arylthio- and 3-alkylthiooxindoles to nitroolefins catalyzed by a simple cinchona alkaloid derived phosphoramide

AU - Gao, Wei Ming

AU - Yu, Jin Sheng

AU - Zhao, Yu Lei

AU - Liu, Yun Lin

AU - Zhou, Feng

AU - Wu, Hai Hong

AU - Zhou, Jian

PY - 2014/11/6

Y1 - 2014/11/6

N2 - A new cinchona alkaloid derived bifunctional tertiary amine-phosphoramide C1e is identified as a highly enantioselective catalyst for Michael addition of both unprotected 3-arylthio- and 3-alkylthiooxindoles to nitroolefins. The phosphoramide moiety of C1e plays an indispensable role in this reaction.

AB - A new cinchona alkaloid derived bifunctional tertiary amine-phosphoramide C1e is identified as a highly enantioselective catalyst for Michael addition of both unprotected 3-arylthio- and 3-alkylthiooxindoles to nitroolefins. The phosphoramide moiety of C1e plays an indispensable role in this reaction.

UR - https://www.scopus.com/pages/publications/84910051219

U2 - 10.1039/c4cc06417h

DO - 10.1039/c4cc06417h

M3 - 文章

C2 - 25335923

AN - SCOPUS:84910051219

SN - 1359-7345

VL - 50

SP - 15179

EP - 15182

JO - Chemical Communications

JF - Chemical Communications

IS - 96

ER -

Highly enantioselective michael addition of 3-arylthio- and 3-alkylthiooxindoles to nitroolefins catalyzed by a simple cinchona alkaloid derived phosphoramide

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