Generation of MnO                         2                          nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione

Qingsong Yang; Li Li; Fang Zhao; Yunwei Wang; Zhishuang Ye; Xuhong Guo

doi:10.1016/j.matlet.2019.04.007

Generation of MnO ₂ nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione

Qingsong Yang
, Li Li^*
, Fang Zhao
, Yunwei Wang
, Zhishuang Ye
, Xuhong Guo

^*此作品的通讯作者

科研成果: 期刊稿件 › 文章 › 同行评审

29 引用（Scopus）

摘要

Novel MnO ₂ nanozymes were prepared as nanosheets in situ using spherical poly[(2-methacryloyloxyethyl) trimethyl ammonium chloride] (PDMC) brushes (SPB) as nanoreactors. The prepared MnO ₂ nanozymes were immobilized in SPB (SPB-MnO ₂ ) showing high stability and excellent oxidase-like property which could oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB), accompanied by the change of absorption at 653 nm. The MnO ₂ nanosheets could be decomposed by trace amount of glutathione (GSH) under acidic environment as validated by small angle X-ray scattering (SAXS). The SPB-MnO ₂ /TMB system, with a detection limit of 450 nM, should be an ideal candidate for colorimetric detection of GSH. This work opens a new way to prepare highly stable nanozymes for the detection of GSH.

源语言	英语
页（从-至）	89-92
页数	4
期刊	Materials Letters
卷	248
DOI	https://doi.org/10.1016/j.matlet.2019.04.007
出版状态	已出版 - 1 8月 2019
已对外发布	是

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10.1016/j.matlet.2019.04.007

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title = " Generation of MnO 2 nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione ",

abstract = " Novel MnO 2 nanozymes were prepared as nanosheets in situ using spherical poly[(2-methacryloyloxyethyl) trimethyl ammonium chloride] (PDMC) brushes (SPB) as nanoreactors. The prepared MnO 2 nanozymes were immobilized in SPB (SPB-MnO 2 ) showing high stability and excellent oxidase-like property which could oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB), accompanied by the change of absorption at 653 nm. The MnO 2 nanosheets could be decomposed by trace amount of glutathione (GSH) under acidic environment as validated by small angle X-ray scattering (SAXS). The SPB-MnO 2 /TMB system, with a detection limit of 450 nM, should be an ideal candidate for colorimetric detection of GSH. This work opens a new way to prepare highly stable nanozymes for the detection of GSH.",

keywords = "MnO nanosheets, Nanocomposites, Nanozyme, Polymers, SAXS, Spherical polyelectrolyte brush",

author = "Qingsong Yang and Li Li and Fang Zhao and Yunwei Wang and Zhishuang Ye and Xuhong Guo",

note = "Publisher Copyright: {\textcopyright} 2019",

year = "2019",

month = aug,

day = "1",

doi = "10.1016/j.matlet.2019.04.007",

language = "英语",

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T1 - Generation of MnO 2 nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione

AU - Yang, Qingsong

AU - Li, Li

AU - Zhao, Fang

AU - Wang, Yunwei

AU - Ye, Zhishuang

AU - Guo, Xuhong

PY - 2019/8/1

Y1 - 2019/8/1

N2 - Novel MnO 2 nanozymes were prepared as nanosheets in situ using spherical poly[(2-methacryloyloxyethyl) trimethyl ammonium chloride] (PDMC) brushes (SPB) as nanoreactors. The prepared MnO 2 nanozymes were immobilized in SPB (SPB-MnO 2 ) showing high stability and excellent oxidase-like property which could oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB), accompanied by the change of absorption at 653 nm. The MnO 2 nanosheets could be decomposed by trace amount of glutathione (GSH) under acidic environment as validated by small angle X-ray scattering (SAXS). The SPB-MnO 2 /TMB system, with a detection limit of 450 nM, should be an ideal candidate for colorimetric detection of GSH. This work opens a new way to prepare highly stable nanozymes for the detection of GSH.

AB - Novel MnO 2 nanozymes were prepared as nanosheets in situ using spherical poly[(2-methacryloyloxyethyl) trimethyl ammonium chloride] (PDMC) brushes (SPB) as nanoreactors. The prepared MnO 2 nanozymes were immobilized in SPB (SPB-MnO 2 ) showing high stability and excellent oxidase-like property which could oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB), accompanied by the change of absorption at 653 nm. The MnO 2 nanosheets could be decomposed by trace amount of glutathione (GSH) under acidic environment as validated by small angle X-ray scattering (SAXS). The SPB-MnO 2 /TMB system, with a detection limit of 450 nM, should be an ideal candidate for colorimetric detection of GSH. This work opens a new way to prepare highly stable nanozymes for the detection of GSH.

KW - MnO nanosheets

KW - Nanocomposites

KW - Nanozyme

KW - Polymers

KW - SAXS

KW - Spherical polyelectrolyte brush

UR - https://www.scopus.com/pages/publications/85063795161

U2 - 10.1016/j.matlet.2019.04.007

DO - 10.1016/j.matlet.2019.04.007

M3 - 文章

AN - SCOPUS:85063795161

SN - 0167-577X

VL - 248

SP - 89

EP - 92

JO - Materials Letters

JF - Materials Letters

ER -

Generation of MnO 2 nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione

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Generation of MnO ₂ nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione