Four-Component Ring-Opening Reaction of Pyrroles via C-N Bond Cleavage under Multiple Functions of Elemental Sulfur

Zongkang Wang; Ye Wang; Yang Yuan; Yingge Gu; Yilin Zhu; Lijie Liu; Ziyi Zhuang; Lingkai Kong; Yanzhong Li

doi:10.1021/acs.orglett.3c00945

Four-Component Ring-Opening Reaction of Pyrroles via C-N Bond Cleavage under Multiple Functions of Elemental Sulfur

Zongkang Wang
, Ye Wang
, Yang Yuan
, Yingge Gu
, Yilin Zhu
, Lijie Liu
, Ziyi Zhuang
, Lingkai Kong^*
, Yanzhong Li^*

^*此作品的通讯作者

化学与分子工程学院

East China Normal University
Linyi University

科研成果: 期刊稿件 › 文章 › 同行评审

7 引用（Scopus）

摘要

We report a four-component ring-opening reaction of pyrroles via C-N bond cleavage. In this process, elemental sulfur is used as the sulfur source of thiazole and thioamide and the reductant of olefin. A series of benzothiazoles functionalized with thiopropionamides at the C2 position were synthesized using this method. A plausible reaction mechanism is proposed based on the concise control experiments.

源语言	英语
页（从-至）	3094-3098
页数	5
期刊	Organic Letters
卷	25
期	17
DOI	https://doi.org/10.1021/acs.orglett.3c00945
出版状态	已出版 - 5 5月 2023

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10.1021/acs.orglett.3c00945

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title = "Four-Component Ring-Opening Reaction of Pyrroles via C-N Bond Cleavage under Multiple Functions of Elemental Sulfur",

abstract = "We report a four-component ring-opening reaction of pyrroles via C-N bond cleavage. In this process, elemental sulfur is used as the sulfur source of thiazole and thioamide and the reductant of olefin. A series of benzothiazoles functionalized with thiopropionamides at the C2 position were synthesized using this method. A plausible reaction mechanism is proposed based on the concise control experiments.",

author = "Zongkang Wang and Ye Wang and Yang Yuan and Yingge Gu and Yilin Zhu and Lijie Liu and Ziyi Zhuang and Lingkai Kong and Yanzhong Li",

note = "Publisher Copyright: {\textcopyright} 2023 American Chemical Society",

year = "2023",

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doi = "10.1021/acs.orglett.3c00945",

language = "英语",

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TY - JOUR

T1 - Four-Component Ring-Opening Reaction of Pyrroles via C-N Bond Cleavage under Multiple Functions of Elemental Sulfur

AU - Wang, Zongkang

AU - Wang, Ye

AU - Yuan, Yang

AU - Gu, Yingge

AU - Zhu, Yilin

AU - Liu, Lijie

AU - Zhuang, Ziyi

AU - Kong, Lingkai

AU - Li, Yanzhong

PY - 2023/5/5

Y1 - 2023/5/5

N2 - We report a four-component ring-opening reaction of pyrroles via C-N bond cleavage. In this process, elemental sulfur is used as the sulfur source of thiazole and thioamide and the reductant of olefin. A series of benzothiazoles functionalized with thiopropionamides at the C2 position were synthesized using this method. A plausible reaction mechanism is proposed based on the concise control experiments.

AB - We report a four-component ring-opening reaction of pyrroles via C-N bond cleavage. In this process, elemental sulfur is used as the sulfur source of thiazole and thioamide and the reductant of olefin. A series of benzothiazoles functionalized with thiopropionamides at the C2 position were synthesized using this method. A plausible reaction mechanism is proposed based on the concise control experiments.

UR - https://www.scopus.com/pages/publications/85156237827

U2 - 10.1021/acs.orglett.3c00945

DO - 10.1021/acs.orglett.3c00945

M3 - 文章

C2 - 37087758

AN - SCOPUS:85156237827

SN - 1523-7060

VL - 25

SP - 3094

EP - 3098

JO - Organic Letters

JF - Organic Letters

IS - 17

ER -

Four-Component Ring-Opening Reaction of Pyrroles via C-N Bond Cleavage under Multiple Functions of Elemental Sulfur

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