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Development of cell microarray by using superhydrophilic silicon dioxide nano structure

  • CAS - Shanghai Institute of Microsystem and Information Technology
  • University of Chinese Academy of Sciences

科研成果: 书/报告/会议事项章节 › 会议稿件 › 同行评审

摘要

Studies on cellular behaviors on substrates with various physicochemical properties have important implications in cytology and bio-medical field. And a variety of cell microarrays have been developed to study in vitro. Our study aims to explore the relations between nano silicon dioxide structure substrates and circulating tumor cells (CTCs) adhesion, and create cell microarrays based on the cell adhesions with the substrate. The method for the preparation of microarray presented herein is based on creating a superhydrophilic array by DRIE technology and thermal oxidation. Superhydrophilic microarrays were achieved as a convex array on SOI wafer. The extreme wettability of the superhydrophilic arrays guaranteed an easy and homogeneous adsorption of the cells, while flat silicon dioxide barriers effectively prevented cross-contamination of the cells.

源语言英语
主期刊名16th International Conference on Nanotechnology - IEEE NANO 2016
出版商Institute of Electrical and Electronics Engineers Inc.
页238-240
页数3
ISBN(电子版)9781509039142
DOI
出版状态已出版 - 21 11月 2016
已对外发布是
活动16th IEEE International Conference on Nanotechnology - IEEE NANO 2016 - Sendai, 日本
期限: 22 8月 2016 → 25 8月 2016

丛书

姓名16th International Conference on Nanotechnology - IEEE NANO 2016

会议

会议16th IEEE International Conference on Nanotechnology - IEEE NANO 2016
国家/地区日本
市Sendai
时期22/08/16 → 25/08/16

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