Design and synthesis of new Imatinib analogs containing thiazolyl moiety

Yu Luo; Haiyan Liu; Wei Lu

doi:10.1002/jhet.1055

Design and synthesis of new Imatinib analogs containing thiazolyl moiety

Yu Luo
, Haiyan Liu
, Wei Lu

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

1 引用（Scopus）

摘要

A series of thiazolyl moiety-containing pyrimidine derivatives were synthesized and evaluated for their cytotoxicity against chronic myelogenous leukemia cell line K562 and human breast cancer cell line MCF-7. Most compounds showed good antiproliferation activity.

源语言	英语
页（从-至）	1357-1362
页数	6
期刊	Journal of Heterocyclic Chemistry
卷	50
期	6
DOI	https://doi.org/10.1002/jhet.1055
出版状态	已出版 - 11月 2013

联合国可持续发展目标

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可持续发展目标 3 良好健康与福祉

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10.1002/jhet.1055

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引用此

@article{53776801abca41c88ce5419fc18f385d,

title = "Design and synthesis of new Imatinib analogs containing thiazolyl moiety",

abstract = "A series of thiazolyl moiety-containing pyrimidine derivatives were synthesized and evaluated for their cytotoxicity against chronic myelogenous leukemia cell line K562 and human breast cancer cell line MCF-7. Most compounds showed good antiproliferation activity.",

author = "Yu Luo and Haiyan Liu and Wei Lu",

year = "2013",

month = nov,

doi = "10.1002/jhet.1055",

language = "英语",

volume = "50",

pages = "1357--1362",

journal = "Journal of Heterocyclic Chemistry",

issn = "0022-152X",

publisher = "John Wiley and Sons Inc",

number = "6",

}

TY - JOUR

T1 - Design and synthesis of new Imatinib analogs containing thiazolyl moiety

AU - Luo, Yu

AU - Liu, Haiyan

AU - Lu, Wei

PY - 2013/11

Y1 - 2013/11

N2 - A series of thiazolyl moiety-containing pyrimidine derivatives were synthesized and evaluated for their cytotoxicity against chronic myelogenous leukemia cell line K562 and human breast cancer cell line MCF-7. Most compounds showed good antiproliferation activity.

AB - A series of thiazolyl moiety-containing pyrimidine derivatives were synthesized and evaluated for their cytotoxicity against chronic myelogenous leukemia cell line K562 and human breast cancer cell line MCF-7. Most compounds showed good antiproliferation activity.

UR - https://www.scopus.com/pages/publications/84888642289

U2 - 10.1002/jhet.1055

DO - 10.1002/jhet.1055

M3 - 文章

AN - SCOPUS:84888642289

SN - 0022-152X

VL - 50

SP - 1357

EP - 1362

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

IS - 6

ER -

Design and synthesis of new Imatinib analogs containing thiazolyl moiety

摘要

联合国可持续发展目标

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