Coordination-drIVen self-assembly of a Pt(IV) prodrug-conjugated supramolecular hexagon

Zhizhou Yue; Han Wang; Yiming Li; Yi Qin; Lin Xu; David J. Bowers; Mahinda Gangoda; Xiaopeng Li; Hai Bo Yang; Yao Rong Zheng

doi:10.1039/c7cc07622c

Coordination-drIVen self-assembly of a Pt(IV) prodrug-conjugated supramolecular hexagon

Zhizhou Yue
, Han Wang
, Yiming Li
, Yi Qin
, Lin Xu
, David J. Bowers
, Mahinda Gangoda
, Xiaopeng Li
, Hai Bo Yang
, Yao Rong Zheng^*

^*此作品的通讯作者

化学与分子工程学院

Kent State University
University of South Florida
East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

49 引用（Scopus）

摘要

This article presents a new strategy to engage coordination-driven self-assembly for platinum drug delivery. The self-assembled supramolecular hexagon is conjugated with three equivalents of Pt(iv) prodrugs and displays a superior therapeutic index compared to cisplatin against a panel of human cancer cell lines.

源语言	英语
页（从-至）	731-734
页数	4
期刊	Chemical Communications
卷	54
期	7
DOI	https://doi.org/10.1039/c7cc07622c
出版状态	已出版 - 2018

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

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10.1039/c7cc07622c

其它文件与链接

链接到 Scopus 的出版物

引用此

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title = "Coordination-drIVen self-assembly of a Pt(IV) prodrug-conjugated supramolecular hexagon",

abstract = "This article presents a new strategy to engage coordination-driven self-assembly for platinum drug delivery. The self-assembled supramolecular hexagon is conjugated with three equivalents of Pt(iv) prodrugs and displays a superior therapeutic index compared to cisplatin against a panel of human cancer cell lines.",

author = "Zhizhou Yue and Han Wang and Yiming Li and Yi Qin and Lin Xu and Bowers, \{David J.\} and Mahinda Gangoda and Xiaopeng Li and Yang, \{Hai Bo\} and Zheng, \{Yao Rong\}",

note = "Publisher Copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/c7cc07622c",

language = "英语",

volume = "54",

pages = "731--734",

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TY - JOUR

T1 - Coordination-drIVen self-assembly of a Pt(IV) prodrug-conjugated supramolecular hexagon

AU - Yue, Zhizhou

AU - Wang, Han

AU - Li, Yiming

AU - Qin, Yi

AU - Xu, Lin

AU - Bowers, David J.

AU - Gangoda, Mahinda

AU - Li, Xiaopeng

AU - Yang, Hai Bo

AU - Zheng, Yao Rong

PY - 2018

Y1 - 2018

N2 - This article presents a new strategy to engage coordination-driven self-assembly for platinum drug delivery. The self-assembled supramolecular hexagon is conjugated with three equivalents of Pt(iv) prodrugs and displays a superior therapeutic index compared to cisplatin against a panel of human cancer cell lines.

AB - This article presents a new strategy to engage coordination-driven self-assembly for platinum drug delivery. The self-assembled supramolecular hexagon is conjugated with three equivalents of Pt(iv) prodrugs and displays a superior therapeutic index compared to cisplatin against a panel of human cancer cell lines.

UR - https://www.scopus.com/pages/publications/85040983607

U2 - 10.1039/c7cc07622c

DO - 10.1039/c7cc07622c

M3 - 文章

C2 - 29303526

AN - SCOPUS:85040983607

SN - 1359-7345

VL - 54

SP - 731

EP - 734

JO - Chemical Communications

JF - Chemical Communications

IS - 7

ER -

Coordination-drIVen self-assembly of a Pt(IV) prodrug-conjugated supramolecular hexagon

摘要

联合国可持续发展目标

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其它文件与链接

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