Convenient synthesis of sorafenib and its derivatives

Lijuan Zhang; Wenpin Xia; Bo Wang; Yu Luo; Wei Lu

doi:10.1080/00397911.2010.517372

Convenient synthesis of sorafenib and its derivatives

Lijuan Zhang
, Wenpin Xia
, Bo Wang
, Yu Luo^*
, Wei Lu

^*此作品的通讯作者

化学与分子工程学院

East China Normal University
Shanghai Pu Yi Chem-Tech. Co., Ltd.

科研成果: 期刊稿件 › 文章 › 同行评审

21 引用（Scopus）

摘要

This article describes a convenient synthesis of sorafinib and its derivatives from phenyl carbamates in good yields. This procedure, avoiding toxic phosgene, is especially suitable for large-scale preparation.

源语言	英语
页（从-至）	3140-3146
页数	7
期刊	Synthetic Communications
卷	41
期	21
DOI	https://doi.org/10.1080/00397911.2010.517372
出版状态	已出版 - 1月 2011

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@article{6257b83a32374c32b633c9bb269ab8f6,

title = "Convenient synthesis of sorafenib and its derivatives",

abstract = "This article describes a convenient synthesis of sorafinib and its derivatives from phenyl carbamates in good yields. This procedure, avoiding toxic phosgene, is especially suitable for large-scale preparation.",

keywords = "Aminolysis, phenyl carbamate, sorafenib, unsymmetrical urea",

author = "Lijuan Zhang and Wenpin Xia and Bo Wang and Yu Luo and Wei Lu",

year = "2011",

month = jan,

doi = "10.1080/00397911.2010.517372",

language = "英语",

volume = "41",

pages = "3140--3146",

journal = "Synthetic Communications",

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TY - JOUR

T1 - Convenient synthesis of sorafenib and its derivatives

AU - Zhang, Lijuan

AU - Xia, Wenpin

AU - Wang, Bo

AU - Luo, Yu

AU - Lu, Wei

PY - 2011/1

Y1 - 2011/1

N2 - This article describes a convenient synthesis of sorafinib and its derivatives from phenyl carbamates in good yields. This procedure, avoiding toxic phosgene, is especially suitable for large-scale preparation.

AB - This article describes a convenient synthesis of sorafinib and its derivatives from phenyl carbamates in good yields. This procedure, avoiding toxic phosgene, is especially suitable for large-scale preparation.

KW - Aminolysis

KW - phenyl carbamate

KW - sorafenib

KW - unsymmetrical urea

UR - https://www.scopus.com/pages/publications/79960630626

U2 - 10.1080/00397911.2010.517372

DO - 10.1080/00397911.2010.517372

M3 - 文章

AN - SCOPUS:79960630626

SN - 0039-7911

VL - 41

SP - 3140

EP - 3146

JO - Synthetic Communications

JF - Synthetic Communications

IS - 21

ER -

Convenient synthesis of sorafenib and its derivatives

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