Cobalt-catalyzed regioselective syntheses of indeno[2,1-: C] pyridines from nitriles and diynes bearing propargyl fragments

Murong Xu; Zhong Zheng; Mengdan Wang; Lingkai Kong; Yujuan Ao; Yanzhong Li

doi:10.1039/c8ob02419g

Cobalt-catalyzed regioselective syntheses of indeno[2,1-: C] pyridines from nitriles and diynes bearing propargyl fragments

Murong Xu
, Zhong Zheng
, Mengdan Wang
, Lingkai Kong
, Yujuan Ao
, Yanzhong Li^*

^*此作品的通讯作者

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

9 引用（Scopus）

摘要

A highly efficient CoI ₂ /o-phenanthroline catalyzed cycloaddition reaction of diynes bearing TBS protected propargylic alcohol fragments with nitriles has been developed. This methodology offers regioselective access, with good functional group tolerance, to various indeno[2,1-c]pyridine derivatives in moderate to excellent yields. It was found that o-phenanthroline as a bidentate nitrogen ligand showed high efficacy in this cycloaddition reaction.

源语言	英语
页（从-至）	8761-8768
页数	8
期刊	Organic and Biomolecular Chemistry
卷	16
期	45
DOI	https://doi.org/10.1039/c8ob02419g
出版状态	已出版 - 2018

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title = "Cobalt-catalyzed regioselective syntheses of indeno[2,1-: C] pyridines from nitriles and diynes bearing propargyl fragments",

abstract = " A highly efficient CoI 2 /o-phenanthroline catalyzed cycloaddition reaction of diynes bearing TBS protected propargylic alcohol fragments with nitriles has been developed. This methodology offers regioselective access, with good functional group tolerance, to various indeno[2,1-c]pyridine derivatives in moderate to excellent yields. It was found that o-phenanthroline as a bidentate nitrogen ligand showed high efficacy in this cycloaddition reaction.",

author = "Murong Xu and Zhong Zheng and Mengdan Wang and Lingkai Kong and Yujuan Ao and Yanzhong Li",

note = "Publisher Copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/c8ob02419g",

language = "英语",

volume = "16",

pages = "8761--8768",

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T1 - Cobalt-catalyzed regioselective syntheses of indeno[2,1-

T2 - C] pyridines from nitriles and diynes bearing propargyl fragments

AU - Xu, Murong

AU - Zheng, Zhong

AU - Wang, Mengdan

AU - Kong, Lingkai

AU - Ao, Yujuan

AU - Li, Yanzhong

PY - 2018

Y1 - 2018

N2 - A highly efficient CoI 2 /o-phenanthroline catalyzed cycloaddition reaction of diynes bearing TBS protected propargylic alcohol fragments with nitriles has been developed. This methodology offers regioselective access, with good functional group tolerance, to various indeno[2,1-c]pyridine derivatives in moderate to excellent yields. It was found that o-phenanthroline as a bidentate nitrogen ligand showed high efficacy in this cycloaddition reaction.

AB - A highly efficient CoI 2 /o-phenanthroline catalyzed cycloaddition reaction of diynes bearing TBS protected propargylic alcohol fragments with nitriles has been developed. This methodology offers regioselective access, with good functional group tolerance, to various indeno[2,1-c]pyridine derivatives in moderate to excellent yields. It was found that o-phenanthroline as a bidentate nitrogen ligand showed high efficacy in this cycloaddition reaction.

UR - https://www.scopus.com/pages/publications/85056803230

U2 - 10.1039/c8ob02419g

DO - 10.1039/c8ob02419g

M3 - 文章

C2 - 30402643

AN - SCOPUS:85056803230

SN - 1477-0520

VL - 16

SP - 8761

EP - 8768

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 45

ER -

Cobalt-catalyzed regioselective syntheses of indeno[2,1-: C] pyridines from nitriles and diynes bearing propargyl fragments

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