Catalytic asymmetric reductive animation of α-branched ketones

Vijay N. Wakchaure; Jian Zhou; Sebastian Hoffmann; Benjamin List

doi:10.1002/anie.201001715

Catalytic asymmetric reductive animation of α-branched ketones

Vijay N. Wakchaure
, Jian Zhou
, Sebastian Hoffmann
, Benjamin List

Max Planck Institute for Coal Research

科研成果: 期刊稿件 › 文章 › 同行评审

135 引用（Scopus）

摘要

Chemical equcation Presented Branching out: An organocatalytic reductive amination of -αbranched ketones using dynamic kinetic resolution is reported. The e/s-2-substituted cyclohexyl amines were obtained in high diastereoselectivity and enantioselectivity from the corresponding ketones.

源语言	英语
页（从-至）	4612-4614
页数	3
期刊	Angewandte Chemie - International Edition
卷	49
期	27
DOI	https://doi.org/10.1002/anie.201001715
出版状态	已出版 - 21 6月 2010
已对外发布	是

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abstract = "Chemical equcation Presented Branching out: An organocatalytic reductive amination of -αbranched ketones using dynamic kinetic resolution is reported. The e/s-2-substituted cyclohexyl amines were obtained in high diastereoselectivity and enantioselectivity from the corresponding ketones.",

keywords = "Asymmetric catalysis, Chiral amines, Ketones, Organocatalysis, Reductive amination",

author = "Wakchaure, \{Vijay N.\} and Jian Zhou and Sebastian Hoffmann and Benjamin List",

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AU - Wakchaure, Vijay N.

AU - Zhou, Jian

AU - Hoffmann, Sebastian

AU - List, Benjamin

PY - 2010/6/21

Y1 - 2010/6/21

N2 - Chemical equcation Presented Branching out: An organocatalytic reductive amination of -αbranched ketones using dynamic kinetic resolution is reported. The e/s-2-substituted cyclohexyl amines were obtained in high diastereoselectivity and enantioselectivity from the corresponding ketones.

AB - Chemical equcation Presented Branching out: An organocatalytic reductive amination of -αbranched ketones using dynamic kinetic resolution is reported. The e/s-2-substituted cyclohexyl amines were obtained in high diastereoselectivity and enantioselectivity from the corresponding ketones.

KW - Asymmetric catalysis

KW - Chiral amines

KW - Ketones

KW - Organocatalysis

KW - Reductive amination

UR - https://www.scopus.com/pages/publications/77953948379

U2 - 10.1002/anie.201001715

DO - 10.1002/anie.201001715

M3 - 文章

AN - SCOPUS:77953948379

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VL - 49

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JO - Angewandte Chemie - International Edition

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Catalytic asymmetric reductive animation of α-branched ketones

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