Catalytic acylcyanation of imines with acetylcyanide

Subhas Chandra Pan; Jian Zhou; Benjamin List

doi:10.1055/s-2006-951543

Catalytic acylcyanation of imines with acetylcyanide

Subhas Chandra Pan
, Jian Zhou
, Benjamin List^*

^*此作品的通讯作者

Max Planck Institute for Coal Research

科研成果: 期刊稿件 › 文章 › 同行评审

37 引用（Scopus）

摘要

Aldimines react with acetyl cyanide in the presence of a catalytic amount of a thiourea catalyst to give the corresponding N-acetylated amino nitriles in high yields. The scope of the reaction is broad and both aromatic as well as aliphatic aldimines can readily be used.

源语言	英语
页（从-至）	3275-3276
页数	2
期刊	Synlett
期	19
DOI	https://doi.org/10.1055/s-2006-951543
出版状态	已出版 - 1 12月 2006
已对外发布	是

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@article{b6885c9598ab4d068cdca3d443146be9,

title = "Catalytic acylcyanation of imines with acetylcyanide",

abstract = "Aldimines react with acetyl cyanide in the presence of a catalytic amount of a thiourea catalyst to give the corresponding N-acetylated amino nitriles in high yields. The scope of the reaction is broad and both aromatic as well as aliphatic aldimines can readily be used.",

keywords = "Acetyl cyanide, Acylcyanation, Br{\o}nsted acid catalysis, Organocatalysis, α-amino nitrile",

author = "Pan, \{Subhas Chandra\} and Jian Zhou and Benjamin List",

year = "2006",

month = dec,

day = "1",

doi = "10.1055/s-2006-951543",

language = "英语",

pages = "3275--3276",

journal = "Synlett",

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TY - JOUR

T1 - Catalytic acylcyanation of imines with acetylcyanide

AU - Pan, Subhas Chandra

AU - Zhou, Jian

AU - List, Benjamin

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Aldimines react with acetyl cyanide in the presence of a catalytic amount of a thiourea catalyst to give the corresponding N-acetylated amino nitriles in high yields. The scope of the reaction is broad and both aromatic as well as aliphatic aldimines can readily be used.

AB - Aldimines react with acetyl cyanide in the presence of a catalytic amount of a thiourea catalyst to give the corresponding N-acetylated amino nitriles in high yields. The scope of the reaction is broad and both aromatic as well as aliphatic aldimines can readily be used.

KW - Acetyl cyanide

KW - Acylcyanation

KW - Brønsted acid catalysis

KW - Organocatalysis

KW - α-amino nitrile

UR - https://www.scopus.com/pages/publications/33845634715

U2 - 10.1055/s-2006-951543

DO - 10.1055/s-2006-951543

M3 - 文章

AN - SCOPUS:33845634715

SN - 0936-5214

SP - 3275

EP - 3276

JO - Synlett

JF - Synlett

IS - 19

ER -

Catalytic acylcyanation of imines with acetylcyanide

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