Calcium doped mesoporous silica nanoparticles as efficient alendronate delivery vehicles

Jinlou Gu; Meng Huang; Jiapeng Liu; Yongsheng Li; Wenru Zhao; Jianlin Shi

doi:10.1039/c2nj40482f

Calcium doped mesoporous silica nanoparticles as efficient alendronate delivery vehicles

Jinlou Gu^*
, Meng Huang
, Jiapeng Liu
, Yongsheng Li
, Wenru Zhao
, Jianlin Shi

^*此作品的通讯作者

East China University of Science and Technology
CAS - Shanghai Institute of Ceramics

科研成果: 期刊稿件 › 文章 › 同行评审

28 引用（Scopus）

摘要

Calcium doped mesoporous silica nanoparticles were successfully prepared and employed as efficient drug carriers for alendronate delivery. The incorporation of calcium ions dramatically enhanced the drug loading capacity and sustained release rate. The loaded alendronate more efficiently inhibited the growth of HeLa cancer cells than free drug.

源语言	英语
页（从-至）	1717-1720
页数	4
期刊	New Journal of Chemistry
卷	36
期	9
DOI	https://doi.org/10.1039/c2nj40482f
出版状态	已出版 - 9月 2012
已对外发布	是

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

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@article{19785c820b27460e9fcf1fc2cd874c1f,

title = "Calcium doped mesoporous silica nanoparticles as efficient alendronate delivery vehicles",

abstract = "Calcium doped mesoporous silica nanoparticles were successfully prepared and employed as efficient drug carriers for alendronate delivery. The incorporation of calcium ions dramatically enhanced the drug loading capacity and sustained release rate. The loaded alendronate more efficiently inhibited the growth of HeLa cancer cells than free drug.",

author = "Jinlou Gu and Meng Huang and Jiapeng Liu and Yongsheng Li and Wenru Zhao and Jianlin Shi",

year = "2012",

month = sep,

doi = "10.1039/c2nj40482f",

language = "英语",

volume = "36",

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TY - JOUR

T1 - Calcium doped mesoporous silica nanoparticles as efficient alendronate delivery vehicles

AU - Gu, Jinlou

AU - Huang, Meng

AU - Liu, Jiapeng

AU - Li, Yongsheng

AU - Zhao, Wenru

AU - Shi, Jianlin

PY - 2012/9

Y1 - 2012/9

N2 - Calcium doped mesoporous silica nanoparticles were successfully prepared and employed as efficient drug carriers for alendronate delivery. The incorporation of calcium ions dramatically enhanced the drug loading capacity and sustained release rate. The loaded alendronate more efficiently inhibited the growth of HeLa cancer cells than free drug.

AB - Calcium doped mesoporous silica nanoparticles were successfully prepared and employed as efficient drug carriers for alendronate delivery. The incorporation of calcium ions dramatically enhanced the drug loading capacity and sustained release rate. The loaded alendronate more efficiently inhibited the growth of HeLa cancer cells than free drug.

UR - https://www.scopus.com/pages/publications/84865116926

U2 - 10.1039/c2nj40482f

DO - 10.1039/c2nj40482f

M3 - 文章

AN - SCOPUS:84865116926

SN - 1144-0546

VL - 36

SP - 1717

EP - 1720

JO - New Journal of Chemistry

JF - New Journal of Chemistry

IS - 9

ER -

Calcium doped mesoporous silica nanoparticles as efficient alendronate delivery vehicles

摘要

联合国可持续发展目标

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