Brønsted acid catalysed chemo- andortho-selective aminomethylation of phenol

Zhiqiong Tang; Dongdong Li; Yidi Yue; Dan Peng; Lu Liu

doi:10.1039/d1ob00820j

Brønsted acid catalysed chemo- andortho-selective aminomethylation of phenol

Zhiqiong Tang
, Dongdong Li
, Yidi Yue
, Dan Peng
, Lu Liu^*

^*此作品的通讯作者

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

13 引用（Scopus）

摘要

We have developed a Brønsted acid catalysed highlyortho-selective functionalization of free phenols with readily availableN,O-acetals under mild conditions, furnishing various corresponding aminomethylated phenol products in moderate to excellent yields. The salient features of this transformation include mild conditions, good substrate scope, excellentortho-selectivity, high efficiency, and ease of further transformation.

源语言	英语
页（从-至）	5777-5781
页数	5
期刊	Organic and Biomolecular Chemistry
卷	19
期	26
DOI	https://doi.org/10.1039/d1ob00820j
出版状态	已出版 - 14 7月 2021

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10.1039/d1ob00820j

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abstract = "We have developed a Br{\o}nsted acid catalysed highlyortho-selective functionalization of free phenols with readily availableN,O-acetals under mild conditions, furnishing various corresponding aminomethylated phenol products in moderate to excellent yields. The salient features of this transformation include mild conditions, good substrate scope, excellentortho-selectivity, high efficiency, and ease of further transformation.",

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T1 - Brønsted acid catalysed chemo- andortho-selective aminomethylation of phenol

AU - Tang, Zhiqiong

AU - Li, Dongdong

AU - Yue, Yidi

AU - Peng, Dan

AU - Liu, Lu

PY - 2021/7/14

Y1 - 2021/7/14

N2 - We have developed a Brønsted acid catalysed highlyortho-selective functionalization of free phenols with readily availableN,O-acetals under mild conditions, furnishing various corresponding aminomethylated phenol products in moderate to excellent yields. The salient features of this transformation include mild conditions, good substrate scope, excellentortho-selectivity, high efficiency, and ease of further transformation.

AB - We have developed a Brønsted acid catalysed highlyortho-selective functionalization of free phenols with readily availableN,O-acetals under mild conditions, furnishing various corresponding aminomethylated phenol products in moderate to excellent yields. The salient features of this transformation include mild conditions, good substrate scope, excellentortho-selectivity, high efficiency, and ease of further transformation.

UR - https://www.scopus.com/pages/publications/85109268482

U2 - 10.1039/d1ob00820j

DO - 10.1039/d1ob00820j

M3 - 文章

C2 - 34156058

AN - SCOPUS:85109268482

SN - 1477-0520

VL - 19

SP - 5777

EP - 5781

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 26

ER -

Brønsted acid catalysed chemo- andortho-selective aminomethylation of phenol

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