Asymmetric michael addition of ketones to alkylidene malonates and allylidene malonates via enamine - Metal lewis acid bifunctional catalysis

Lu Liu; Ryan Sarkisian; Zhenghu Xu; Hong Wang

doi:10.1021/jo301070s

Asymmetric michael addition of ketones to alkylidene malonates and allylidene malonates via enamine - Metal lewis acid bifunctional catalysis

Lu Liu
, Ryan Sarkisian
, Zhenghu Xu^*
, Hong Wang

^*此作品的通讯作者

Miami University
Shandong University

科研成果: 期刊稿件 › 文章 › 同行评审

33 引用（Scopus）

摘要

Novel enamine-metal Lewis acid bifunctional catalysts were successfully applied to the asymmetric Michael addition of ketones to alkylidene malonates, offering excellent stereoselectivity (up to >99% ee and >99:1 dr). The asymmetric Michael addition of ketones to allylidene malonates was also achieved.

源语言	英语
页（从-至）	7693-7699
页数	7
期刊	Journal of Organic Chemistry
卷	77
期	17
DOI	https://doi.org/10.1021/jo301070s
出版状态	已出版 - 7 9月 2012
已对外发布	是

访问文件

10.1021/jo301070s

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{0df0e4383771476e8bbbd9ba064d39d1,

title = "Asymmetric michael addition of ketones to alkylidene malonates and allylidene malonates via enamine - Metal lewis acid bifunctional catalysis",

abstract = "Novel enamine-metal Lewis acid bifunctional catalysts were successfully applied to the asymmetric Michael addition of ketones to alkylidene malonates, offering excellent stereoselectivity (up to >99\% ee and >99:1 dr). The asymmetric Michael addition of ketones to allylidene malonates was also achieved.",

author = "Lu Liu and Ryan Sarkisian and Zhenghu Xu and Hong Wang",

year = "2012",

month = sep,

day = "7",

doi = "10.1021/jo301070s",

language = "英语",

volume = "77",

pages = "7693--7699",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "17",

}

TY - JOUR

T1 - Asymmetric michael addition of ketones to alkylidene malonates and allylidene malonates via enamine - Metal lewis acid bifunctional catalysis

AU - Liu, Lu

AU - Sarkisian, Ryan

AU - Xu, Zhenghu

AU - Wang, Hong

PY - 2012/9/7

Y1 - 2012/9/7

N2 - Novel enamine-metal Lewis acid bifunctional catalysts were successfully applied to the asymmetric Michael addition of ketones to alkylidene malonates, offering excellent stereoselectivity (up to >99% ee and >99:1 dr). The asymmetric Michael addition of ketones to allylidene malonates was also achieved.

AB - Novel enamine-metal Lewis acid bifunctional catalysts were successfully applied to the asymmetric Michael addition of ketones to alkylidene malonates, offering excellent stereoselectivity (up to >99% ee and >99:1 dr). The asymmetric Michael addition of ketones to allylidene malonates was also achieved.

UR - https://www.scopus.com/pages/publications/84866119352

U2 - 10.1021/jo301070s

DO - 10.1021/jo301070s

M3 - 文章

C2 - 22877155

AN - SCOPUS:84866119352

SN - 0022-3263

VL - 77

SP - 7693

EP - 7699

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 17

ER -

Asymmetric michael addition of ketones to alkylidene malonates and allylidene malonates via enamine - Metal lewis acid bifunctional catalysis

摘要

访问文件

其它文件与链接

指纹

引用此