Amphipathic poly-β-peptides for intracellular protein delivery

Qianyi Ren; Qi Chen; Lanfang Ren; Chuntao Cao; Runhui Liu; Yiyun Cheng

doi:10.1039/d2cc00453d

Amphipathic poly-β-peptides for intracellular protein delivery

Qianyi Ren
, Qi Chen
, Lanfang Ren
, Chuntao Cao
, Runhui Liu^*
, Yiyun Cheng^*

^*此作品的通讯作者

生命科学学院

East China Normal University
East China University of Science and Technology

科研成果: 期刊稿件 › 文章 › 同行评审

9 引用（Scopus）

摘要

A series of amphipathic poly-β-peptides are designed for intracellular protein delivery. The poly-β-peptides with higher molecular weight and hydrophobic contents exhibit higher protein loading and superior delivery efficiency. The lead material efficiently delivers proteins into cells with reserved bioactivity.

源语言	英语
页（从-至）	4320-4323
页数	4
期刊	Chemical Communications
卷	58
期	27
DOI	https://doi.org/10.1039/d2cc00453d
出版状态	已出版 - 8 3月 2022

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10.1039/d2cc00453d

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title = "Amphipathic poly-β-peptides for intracellular protein delivery",

abstract = "A series of amphipathic poly-β-peptides are designed for intracellular protein delivery. The poly-β-peptides with higher molecular weight and hydrophobic contents exhibit higher protein loading and superior delivery efficiency. The lead material efficiently delivers proteins into cells with reserved bioactivity.",

author = "Qianyi Ren and Qi Chen and Lanfang Ren and Chuntao Cao and Runhui Liu and Yiyun Cheng",

note = "Publisher Copyright: {\textcopyright} 2022 The Royal Society of Chemistry",

year = "2022",

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doi = "10.1039/d2cc00453d",

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TY - JOUR

T1 - Amphipathic poly-β-peptides for intracellular protein delivery

AU - Ren, Qianyi

AU - Chen, Qi

AU - Ren, Lanfang

AU - Cao, Chuntao

AU - Liu, Runhui

AU - Cheng, Yiyun

PY - 2022/3/8

Y1 - 2022/3/8

N2 - A series of amphipathic poly-β-peptides are designed for intracellular protein delivery. The poly-β-peptides with higher molecular weight and hydrophobic contents exhibit higher protein loading and superior delivery efficiency. The lead material efficiently delivers proteins into cells with reserved bioactivity.

AB - A series of amphipathic poly-β-peptides are designed for intracellular protein delivery. The poly-β-peptides with higher molecular weight and hydrophobic contents exhibit higher protein loading and superior delivery efficiency. The lead material efficiently delivers proteins into cells with reserved bioactivity.

UR - https://www.scopus.com/pages/publications/85127574505

U2 - 10.1039/d2cc00453d

DO - 10.1039/d2cc00453d

M3 - 文章

C2 - 35293911

AN - SCOPUS:85127574505

SN - 1359-7345

VL - 58

SP - 4320

EP - 4323

JO - Chemical Communications

JF - Chemical Communications

IS - 27

ER -

Amphipathic poly-β-peptides for intracellular protein delivery

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