Acid-catalyzed cascade reactions of enaminones with aldehydes: C-H functionalization to afford 1, 4-dihydropyridines

Jingyu Yang; Chengyu Wang; Xin Xie; Hongfeng Li; Yanzhong Li

doi:10.1002/ejoc.201000607

Acid-catalyzed cascade reactions of enaminones with aldehydes: C-H functionalization to afford 1, 4-dihydropyridines

Jingyu Yang
, Chengyu Wang
, Xin Xie
, Hongfeng Li
, Yanzhong Li^*

^*此作品的通讯作者

化学与分子工程学院

East China Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

71 引用（Scopus）

摘要

An efficient acid-catalyzed approach to the synthesis of functional 1,4-dihydropyridines from the reaction of readily available enaminones with aldehydes has been developed. This methodology was realized by a cascade reaction involving first formation of divinylmethanes and subsequent intramolecular cyclization.

源语言	英语
页（从-至）	4189-4193
页数	5
期刊	European Journal of Organic Chemistry
期	22
DOI	https://doi.org/10.1002/ejoc.201000607
出版状态	已出版 - 8月 2010

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title = "Acid-catalyzed cascade reactions of enaminones with aldehydes: C-H functionalization to afford 1, 4-dihydropyridines",

abstract = "An efficient acid-catalyzed approach to the synthesis of functional 1,4-dihydropyridines from the reaction of readily available enaminones with aldehydes has been developed. This methodology was realized by a cascade reaction involving first formation of divinylmethanes and subsequent intramolecular cyclization.",

keywords = "C-H activation, Cyclization, Domino reactions, Lewis acids, Nitrogen heterocycles",

author = "Jingyu Yang and Chengyu Wang and Xin Xie and Hongfeng Li and Yanzhong Li",

year = "2010",

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doi = "10.1002/ejoc.201000607",

language = "英语",

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T1 - Acid-catalyzed cascade reactions of enaminones with aldehydes

T2 - C-H functionalization to afford 1, 4-dihydropyridines

AU - Yang, Jingyu

AU - Wang, Chengyu

AU - Xie, Xin

AU - Li, Hongfeng

AU - Li, Yanzhong

PY - 2010/8

Y1 - 2010/8

N2 - An efficient acid-catalyzed approach to the synthesis of functional 1,4-dihydropyridines from the reaction of readily available enaminones with aldehydes has been developed. This methodology was realized by a cascade reaction involving first formation of divinylmethanes and subsequent intramolecular cyclization.

AB - An efficient acid-catalyzed approach to the synthesis of functional 1,4-dihydropyridines from the reaction of readily available enaminones with aldehydes has been developed. This methodology was realized by a cascade reaction involving first formation of divinylmethanes and subsequent intramolecular cyclization.

KW - C-H activation

KW - Cyclization

KW - Domino reactions

KW - Lewis acids

KW - Nitrogen heterocycles

UR - https://www.scopus.com/pages/publications/77954986510

U2 - 10.1002/ejoc.201000607

DO - 10.1002/ejoc.201000607

M3 - 文章

AN - SCOPUS:77954986510

SN - 1434-193X

SP - 4189

EP - 4193

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 22

ER -

Acid-catalyzed cascade reactions of enaminones with aldehydes: C-H functionalization to afford 1, 4-dihydropyridines

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