TY - JOUR
T1 - A telomere-to-telomere genome assembly of Chinese water deer (Hydropotes inermis)
AU - Wu, Haotian
AU - Zhao, Hengquan
AU - Chen, Qiuting
AU - Chen, Min
AU - Lu, Ying
N1 - Publisher Copyright:
© The Author(s) 2026.
PY - 2026/12
Y1 - 2026/12
N2 - Hydropotes inermis (Chinese water deer, 2n = 70) is a relatively primitive small Cervidae species naturally distributed along the eastern coast of China and the Korean Peninsula. High-quality genomic resources are essential for investigating its unique adaptive and biological traits. In this study, we assembled the telomere-to-telomere (T2T) gap-free genome of a female H. inermis using PacBio HiFi, Oxford Nanopore Technologies (ONT), and Hi-C sequencing technologies. The assemblies were 3.45 Gb with a contig N50 of 101.09 Mb in size, which were anchored on 35 chromosomes, carrying 60 telomeres and 35 centromeres. Genome annotation annotated 33.36% repetitive sequences and 24,398 protein-coding genes. Comparative analyses with genomes of closely related species confirmed high genome integrity, continuity, and accuracy, supported by a quality value (QV) of 52.56 and a BUSCO completeness of 99.40%. This study provides a valuable genetic resource for H. inermis and serves as an important reference for investigating the evolutionary history of Cervidae.
AB - Hydropotes inermis (Chinese water deer, 2n = 70) is a relatively primitive small Cervidae species naturally distributed along the eastern coast of China and the Korean Peninsula. High-quality genomic resources are essential for investigating its unique adaptive and biological traits. In this study, we assembled the telomere-to-telomere (T2T) gap-free genome of a female H. inermis using PacBio HiFi, Oxford Nanopore Technologies (ONT), and Hi-C sequencing technologies. The assemblies were 3.45 Gb with a contig N50 of 101.09 Mb in size, which were anchored on 35 chromosomes, carrying 60 telomeres and 35 centromeres. Genome annotation annotated 33.36% repetitive sequences and 24,398 protein-coding genes. Comparative analyses with genomes of closely related species confirmed high genome integrity, continuity, and accuracy, supported by a quality value (QV) of 52.56 and a BUSCO completeness of 99.40%. This study provides a valuable genetic resource for H. inermis and serves as an important reference for investigating the evolutionary history of Cervidae.
UR - https://www.scopus.com/pages/publications/105042549182
U2 - 10.1038/s41597-026-07286-0
DO - 10.1038/s41597-026-07286-0
M3 - 文章
C2 - 42014755
AN - SCOPUS:105042549182
SN - 2052-4463
VL - 13
JO - Scientific Data
JF - Scientific Data
IS - 1
M1 - 922
ER -