A ratiometric fluorescent probe based on FRET for imaging Hg2+ ions in living cells

Xiaolin Zhang; Yi Xiao; Xuhong Qian

doi:10.1002/anie.200803246

A ratiometric fluorescent probe based on FRET for imaging Hg²⁺ ions in living cells

Xiaolin Zhang^*
, Yi Xiao
, Xuhong Qian

^*此作品的通讯作者

Dalian University of Technology
East China University of Science and Technology

科研成果: 期刊稿件 › 文章 › 同行评审

815 引用（Scopus）

摘要

(Chemical Equation Presented) Mercury rising: A FRET-based ratiometric probe (see picture; FRET = fluorescence resonance energy transfer) can selectively detect Hg²⁺ ions on the parts-per-billion scale under physiological conditions. The probe undergoes a clear Hg²⁺-induced change in the intensity ratio ofthe two well-separated and equally intense emission bands of dipyrrometheneboron difluoride and rhodamine. Experiments show that the probe can be used in living cells.

源语言	英语
页（从-至）	8025-8029
页数	5
期刊	Angewandte Chemie - International Edition
卷	47
期	42
DOI	https://doi.org/10.1002/anie.200803246
出版状态	已出版 - 6 10月 2008
已对外发布	是

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abstract = "(Chemical Equation Presented) Mercury rising: A FRET-based ratiometric probe (see picture; FRET = fluorescence resonance energy transfer) can selectively detect Hg2+ ions on the parts-per-billion scale under physiological conditions. The probe undergoes a clear Hg2+-induced change in the intensity ratio ofthe two well-separated and equally intense emission bands of dipyrrometheneboron difluoride and rhodamine. Experiments show that the probe can be used in living cells.",

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AU - Zhang, Xiaolin

AU - Xiao, Yi

AU - Qian, Xuhong

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N2 - (Chemical Equation Presented) Mercury rising: A FRET-based ratiometric probe (see picture; FRET = fluorescence resonance energy transfer) can selectively detect Hg2+ ions on the parts-per-billion scale under physiological conditions. The probe undergoes a clear Hg2+-induced change in the intensity ratio ofthe two well-separated and equally intense emission bands of dipyrrometheneboron difluoride and rhodamine. Experiments show that the probe can be used in living cells.

AB - (Chemical Equation Presented) Mercury rising: A FRET-based ratiometric probe (see picture; FRET = fluorescence resonance energy transfer) can selectively detect Hg2+ ions on the parts-per-billion scale under physiological conditions. The probe undergoes a clear Hg2+-induced change in the intensity ratio ofthe two well-separated and equally intense emission bands of dipyrrometheneboron difluoride and rhodamine. Experiments show that the probe can be used in living cells.

KW - FRET

KW - Fluorescent probes

KW - Mercury

KW - Rhodamine

KW - Sensors

UR - https://www.scopus.com/pages/publications/54049138881

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 42

ER -

A ratiometric fluorescent probe based on FRET for imaging Hg2+ ions in living cells

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A ratiometric fluorescent probe based on FRET for imaging Hg²⁺ ions in living cells